Results 51 to 60 of about 7,653 (215)

Combined ovulation triggering with GnRH agonist and hCG in IVF patients [PDF]

, 2016
The aim of the review is to analyse the combination of a gonadotrophin releasing hormone (GnRH) agonist with a human chorionic gonadotrophin (hCG) trigger, for final oocyte maturation in in vitro fertilisation (IVF) cycles.
Kasum, Miro, Kurdija, Kristijan, Orešković, Slavko, Pavičić-Baldani, Dinka, Čehić, Ermin, Škrgatić, Lana   +5 more
core   +1 more source

Artificial lipidation of proteins and peptides: from mechanism to clinical applications

The FEBS Journal, Volume 293, Issue 5, Page 1269-1284, March 2026.
Artificial lipidation transforms protein and peptide therapeutics by attaching fatty acid chains through reversible or permanent chemical strategies. This biomimetic approach delivers four key therapeutic advantages: extended circulation times (enabling weekly instead of daily dosing), alternative administration routes including oral delivery, precise ...
Jiaming Mu, Emily Vong, Sheiliza Carmali
wiley   +1 more source

Evolving strategies in prostate cancer: Emerging approaches and unmet needs from the Bridging the Gaps in Prostate Cancer expert panel

Cancer, Volume 132, Issue 4, 15 February 2026.
Abstract Background The expansion of treatment options for prostate cancer (PC) has improved disease‐specific and overall survival outcomes but has also raised questions about the optimal level of treatment needed for patients based on their individual prognosis and accounting for potential toxicity, incorporating quality of life considerations ...
Rana R. McKay, Benjamin L. Maughan, Alicia K. Morgans, Neal D. Shore, Evan Y. Yu, Ravi A. Madan, Jacob E. Berchuck, Bradley C. Carthon, Steven E. Finkelstein, Leonard Gomella, Michael A. Gorin, Andrew W. Hahn, Stacy Loeb, Vivek K. Narayan, Daniel P. Petrylak, Charles J. Ryan, Karine Tawagi, Phuoc T. Tran, Tanya Dorff   +18 more
wiley   +1 more source

Central Precocious Puberty in an Infant with Sotos Syndrome and Response to Treatment

JCRPE, 2022
Sotos syndrome (SS) is characterized by overgrowth, distinctive facial appearance, and learning disability. It is caused by heterozygous mutations, including deletions of NSD1 located at chromosome 5q35.
Tuğba Kontbay, Zeynep Şıklar, Serdar Ceylaner, Merih Berberoğlu   +3 more
doaj   +1 more source

Androgen receptors beyond prostate cancer: an old marker as a new target. [PDF]

, 2014
Androgen receptors (ARs) play a critical role in the development of prostate cancer. Targeting ARs results in important salutary effects in this malignancy.
Kurzrock, Razelle, Munoz, Javier, Wheler, Jennifer J   +2 more
core   +2 more sources

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, Volume 15, Issue 6, 9 February 2026.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, Volume 13, Issue 10, 18 February 2026.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

Acetato de ulipristal en el tratamiento de los miomas uterinos [PDF]

, 2018
[ES] Los miomas uterinos (MU), o leiomiomas, son tumores monoclonales benignos que surgen a partir de las células del músculo liso del útero, el miometrio; contienen, además, gran cantidad de matriz extracelular con colágeno, proteoglicanos y ...
Martínez Rios, Clara Elisa
core  

A Roadmap for Advancing Women's Health in Disorders of the Gut‐Brain Interaction

United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Disorders of the Gut‐Brain Interaction (DGBI) are highly prevalent conditions that all gastroenterologists encounter in clinical practice. Differences between men and women in the prevalence and symptom burden of DGBI have been well documented in numerous epidemiological and observational studies.
Madison R. Heath, Yuying Luo
wiley   +1 more source