Results 31 to 40 of about 11,042 (167)

Efficacy and safety of Levamisole treatment in clinical presentations of non-hospitalized patients with COVID-19: a double-blind, randomized, controlled trial

BMC Infectious Diseases, 2021
Background Levamisole has shown clinical benefits in the management of COVID-19 via its immunomodulatory effect. However, the exact role of Levamisole effect in clinical status of COVID-19 patients is unknown.
Amirreza Roostaei Firozabad, Zohreh Akhoundi Meybodi, Seyed Ruhollah Mousavinasab, Adeleh Sahebnasagh, Mohsen Gholinataj Jelodar, Iman Karimzadeh, Solomon Habtemariam, Fatemeh Saghafi   +7 more
doaj   +1 more source

Exploring the Efficacy and Safety of Levamisole Hydrochloride against Microcotyle sebastis in Korean Rockfish (Sebastes schlegelii): An In Vitro and In Vivo Approach

Animals, 2023
Parasitic infections pose significant challenges in aquaculture, and the increasing resistance to conventional anthelmintics necessitates the exploration of alternative treatments.
Won-Sik Woo, Gyoungsik Kang, Kyung-Ho Kim, Ha-Jeong Son, Min-Young Sohn, Ji-Hoon Lee, Jung-Soo Seo, Mun-Gyeong Kwon, Chan-Il Park   +8 more
doaj   +1 more source

Exercise‐related microRNAs in Caenorhabditis elegans regulate calcium homeostasis and mitochondrial dynamics: Conserved pathways, divergent microRNAs

The FEBS Journal, EarlyView.
Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia, Jiwang Tang, José C. Casas‐Martinez, Penglin Li, Maria Borja‐Gonzalez, Leo R Quinlan, Katarzyna Goljanek‐Whysall, Brian McDonagh   +7 more
wiley   +1 more source

Compromised DNA replication in gut cells underlies sensitivity to genotoxic stress in the tardigrade Hypsibius exemplaris

The FEBS Journal, EarlyView.
DNA damage in the tardigrade Hypsibius exemplaris elicits distinct cellular outcomes depending on replication status. While non‐replicating cells tolerate genotoxic stress, constitutively replicating cells undergo irreversible replication failure upon DNA damage, leading to loss of tissue homeostasis, fat depletion, sterility, and organismal death ...
Gonzalo Quiroga‐Artigas, Pauline Fontanié, Benjamin Lacroix, Maria Dolores Molina, María Moriel‐Carretero   +4 more
wiley   +1 more source

Comparison of Free and Liposomal Levamisole Antiparasitic Activity in Sheep

Revista Científica
Worldwide, parasitic organisms residing in the digestive systems of sheep cause substantial economic losses. Various antiparasitic chemicals are employed to combat parasites, mostly levamisole.
Mehmet Özüiçli, Hasan Susar, Murat Çelebi, Çağla Çelebi, Hüseyin Şen, İzzet Karahan   +5 more
doaj   +1 more source

Distinctive vasculopathy with systemic involvement due to levamisole long-term therapy: a case report

Journal of Medical Case Reports, 2018
Background Levamisole belongs to the antihelminthic class of drugs that are sometimes administered to patients with frequently relapsing or steroid-dependent nephrotic syndrome, owing to its steroid-sparing effects.
Bilal Aoun, Mohammad Alali, Jad A. Degheili, Sami Sanjad, Claudine Vaquin, Jean Donadieu, Tim Ulinski, Salah Termos   +7 more
doaj   +1 more source

Effect of a Single and Triple Dose of Levamisole on Hematological Parameters in Controlled Inflammation Model

Animals, 2022
This study aimed to evaluate the impact of single and triple administration of levamisole on the dynamics of hematological parameters during experimental pleuritis. The experiment was performed on female Buffalo rats.
Piotr Kuropka, Anna Leśków, Katarzyna Małolepsza-Jarmołowska, Maciej Dobrzyński, Małgorzata Tarnowska, Jacek Majda, Maciej Janeczek, Katarzyna Żybura-Wszoła, Andrzej Gamian   +8 more
doaj   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra, Cecile Wasielewski, Bruno Špiljak, Maja Sabalić‐Schoener, Sebastien Jungo, Ivan Alajbeg   +5 more
wiley   +1 more source

Levamisole adulterated cocaine associated ANCA vasculitis: review of literature and update on pathogenesis

Journal of Community Hospital Internal Medicine Perspectives, 2018
Levamisole is an antihelminth drug and a common cocaine contaminant, present in an estimated 71% of cocaine samples in the US. Levamisole-contaminated cocaine has been linked to an ANCA-associated vasculitis with cutaneous, renal, and pulmonary ...
Qiuyu Jin, Sam Kant, Jihad Alhariri, Duvuru Geetha   +3 more
doaj   +1 more source

Veterinary Pharmaceutical Safety Competencies for New Graduates: Description of an Interprofessional Simulated Learning Activity

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The misuse and abuse of veterinary anesthetic and analgesic agents pose significant public health risks, particularly with the growing presence of ultrapotent opioids and other anesthetics in the illicit drug trade. In response, there is increasing emphasis on incorporating medication safety training into veterinary curricula.
Margene Anderson, Carrie Schroeder, Kristopher M. Schroeder   +2 more
wiley   +1 more source