Results 71 to 80 of about 32,320 (312)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Methodology of research on drivers perception at level crossings

open access: yesMATEC Web of Conferences, 2018
The article presents a proposition of a methodology of research performed to assess car drivers’ perception at level crossings. Its main assumptions as well as the description of devices and tools selected for carrying out the research were given.
Kobaszyńska-Twardowska Anna   +4 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Modelling risk at low-exposure railway level crossings: supporting an argument for low-cost level crossing warning devices with lower levels of safety integrity

open access: yes, 2013
This paper describes a risk model for estimating the likelihood of collisions at low-exposure railway level crossings, demonstrating the effect that differences in safety integrity can have on the likelihood of a collision.
Hughes, Peter   +4 more
core   +1 more source

Application of a Quantitative Risk-Based Decision Tool for Local Railway Level Crossing Management

open access: yesApplied Sciences
Railway level crossings pose risks to both train passengers and road users, worsened by the complex interaction between rail and road traffic, particularly on local railways.
Alessandro Di Graziano   +1 more
doaj   +1 more source

Level crossings and turning points of random hyperbolic polynomials

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1999
In this paper, we show that the asymptotic estimate for the expected number of K-level crossings of a random hyperbolic polynomial a1sinhx+a2sinh2x+⋯+ansinhnx, where aj(j=1,2,…,n) are independent normally distributed random variables with mean zero and ...
K. Farahmand, P. Hannigan
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

On-road driving studies to understand why drivers behave as they do at regional rail level crossings

open access: yes, 2013
Improving safety at rail level crossings is an important part of both road and rail safety strategies. While low in number, crashes between vehicles and trains at level crossings are catastrophic events typically involving multiple fatalities and serious
Salmon, P.B.   +12 more
core  

Driver Compliance With, and Understanding Of, Level Crossing Controls

open access: yesJournal of Road Safety, 2010
Since the early 1970s, in an effort to improve road safety, Australian railway authorities have made a concerted effort to reduce the number of level road-rail crossings, particularly those controlled by passive devices such as ‘give way’ or ‘stop’ signs.
C Rudin-Brown   +5 more
doaj  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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