Results 121 to 130 of about 14,055,750 (308)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Single Particle Level Density in a Harmonic – Oscillator Potential Well

open access: yesIraqi Journal of Physics, 2011
The purpose of this paper is to study the properties of the partial level density ( ) l g and the total level density g ( ), numerically obtained as a l sum of ( ) l g up to 34 max l  , for a Harmonic – Oscillator potential well. This method applied
Mahdi Hadi Jasim
doaj  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Correlations of the current density in many-body Landau level states

open access: yesPhysical Review Research
Motivated by recent advances in quantum gas microscopy, we investigate correlation functions of the current density in many-body Landau level states, such as the Laughlin state of the fractional quantum Hall effect.
Daniel Spasic-Mlacak, Nigel R. Cooper
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Impact of Nuclear Level Density on r-process Rare-earth Peak Nucleosynthesis

open access: yesThe Astrophysical Journal
The rare-earth peak ( A  ∼ 164) is a prominent feature of the r -process, and previous theoretical studies suggest that it is possibly linked to local nuclear structural effects.
Hang Xu   +3 more
doaj   +1 more source

Level-density parameters in superheavy nuclei

open access: yes, 2021
We systematically study the nuclear level densities of superheavy nuclei, including odd systems, using the single-particle energies obtained with the Woods-Saxon potential diagonalization.
Shneidman T.M.   +6 more
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Particle-Hole State Density Calculations with Non-Equidistant Spacing Model: II. Pairing and Exact Treatment

open access: yesIraqi Journal of Physics, 2011
In an earlier paper, the basic analytical formula for particle-hole nuclear state densities was derived for non-Equidistant Spacing Model (non-ESM) approach. In this paper, an extension of the former equation was made to include pairing.
Ahmed Abdul-Razzaq Selman
doaj  

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