Results 71 to 80 of about 2,392,265 (312)

Fast conditional density estimation for quantitative structure-activity relationships [PDF]

, 2010
Many methods for quantitative structure-activity relationships (QSARs) deliver point estimates only, without quantifying the uncertainty inherent in the prediction.
Buchwald, Fabian, Kramer, Stefan, Girschick, Tobias, Frank, Eibe   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Angular momentum dependence of the nuclear level density parameter

EPJ Web of Conferences, 2014
Neutron evaporation spectra alongwith γ-multiplicity has been measured from the 185Re* compound nucleus at the excitation energies ~27 and 37 MeV. Statistical model analysis of the experimental data has been carried out to extract the value of the ...
Gohil M., Roy Pratap, Banerjee K., Bhattacharya S., Bhattacharya C., Kundu S., Rana T. K., Ghosh T. K., Mukherjee G., Pandey R., Meena J. K., Pai H., Srivastava V., Dey A., Pandit Deepak, Mukhopadhyay S., Pal S., Banerjee S. R.   +17 more
doaj   +1 more source

Increased Serum Leptin Level Predicts Bone Mineral Density in Hemodialysis Patients

International Journal of Endocrinology, 2020
Background. Leptin acts through the adipose-bone axis to regulate bone mineral density (BMD). This study evaluated the relationship between BMD and serum leptin levels in patients on hemodialysis. Methods.
Chih-Hsien Wang, Yu-Hsien Lai, Yu-Li Lin, Chiu-Huang Kuo, Ru-Jiang Syu, Ming-Chun Chen, Bang-Gee Hsu   +6 more
doaj   +1 more source

Is negative density‐dependent reproduction regulated by density‐induced stress in root voles? Two field experiments

Ecology and Evolution, 2022
Density dependence in reproduction plays an important role in stabilizing population dynamics via immediate negative feedback from population density to reproductive output.
Guozhen Shang, Shouyang Du, Yanbin Yang, Yan Wu, Yifan Cao, Jianghui Bian   +5 more
doaj   +1 more source

Do social interactions explain ethnic differences in psychological distress and the protective effect of local ethnic density? A cross-sectional study of 226 487 adults in Australia [PDF]

, 2013
Background: A frequently proposed, but under-researched hypothesis is that ethnic density benefits mental health through increasing social interactions.
Astell-Burt, Thomas (R16977), Feng, Xiaoqi (R17108), Feng, Xiaoqi, Astell-Burt, Thomas, Kolt, Gregory S., Kolt, Gregory S. (R11602)   +5 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Particle-Hole State Density Calculations with Non-Equidistant Spacing Model: I. Basic Derivation

Iraqi Journal of Physics, 2010
The basic analytical formula for particle-hole state densities is derived based on the non-Equidistant Spacing Model (non-ESM) for the single-particle level density (s.p.l.d.) dependence on particle excitation energy u.
Ahmed Abdul-Razzaq Selman
doaj  

A novel projected shell model method for nuclear level density [PDF]

EPJ Web of Conferences
We introduce a shell model method for calculating nuclear level density (NLD) generally applicable for arbitrarily heavy deformed nuclei. The method is novel because of our use of physical guidance for the construction of its configuration space and the ...
Sun Yang, Wang Jiaqi, Dutta Saumi, Wang Long-Jun   +3 more
doaj   +1 more source