Results 241 to 250 of about 7,802,667 (305)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Biological Antithrombin III Levels

JAMA: The Journal of the American Medical Association, 1978
To the Editor.— The MEDICAL NEWS article "Automated Test Measures Functional Antithrombin, Coagulation Enzymes" (report of Jayed Fareed, PhD, and Harry L. Mesmore, MD) confirms my observations 1 and those of others 2,3 that there is poor correlation between immunological (total) and functional antithrombin III levels in disease states.
openaire   +2 more sources

Level III: Surfaces

1976
We turn now from molecules and phases to the domain of surfaces — the domain of interfacial phenomena and of colloid chemistry. When we considered molecules on Level I, we thought of them as being exposed to similar molecules on all sides; when we considered phases on Level II, we thought of them as surrounded by more of the same phase or by associated
Theodore George Rochow   +1 more
openaire   +1 more source

Energy levels of Ho III

Physica B+C, 1976
Abstract The early analysis of Ho III has been extended, including parametric studies for complete configurations of 4f11, 4f105d, 4f106s and 4f106p, with 78 new energy levels found, including the lowest even level at 18033.4 cm−11. After optimization of real and effective parameters, the mean deviations on the energies are 32 cm−1 for 72 even levels,
J.F. Wyart   +2 more
openaire   +1 more source

Level III EMCS Hardware

1988
As noted in Chapter 7, Level III systems are divided into “hardware types” based upon the equipment in use: microprocessor- and minicomputer-based systems. In Chapter 8, these hardware types will be distinguished from one another under several headings. These include: Computer Technology Peripheral Devices Field Equipment Software
F. William Payne, John J. McGowan
openaire   +1 more source

Plasma Antithrombin III Levels in Pre-Eclampsia

Clinical and Experimental Hypertension. Part B: Hypertension in Pregnancy, 1983
In a prospective study plasma AT III was determined in 2423 samples obtained from 653 women during pregnancy and post partum. The women were allocated to groups, according to the highest diastolic blood pressure, in the third trimester. AT III levels were normal throughout pregnancy, during labour and after vaginal delivery, except in 57 women with ...
G H, Weenink   +4 more
openaire   +2 more sources

III—Constant-level Ballooning

Journal of Navigation, 1957
For a number of purposes it is convenient to have a platform floating at a constant level high up in the atmosphere. This can be contrived by the use of a special arrangement of balloons for heights up to about 100,000 ft. There are at least three ways in which this can be achieved.
openaire   +1 more source

L‐asparaginase effect on antithrombin‐III levels

Medical and Pediatric Oncology, 1979
AbstractThe effect of L‐asparaginase (L‐asp) therapy on circulating antithrombin‐III (AT‐III) was monitored in three patients with acute lymphoblastic leukemia. Serial determination for AT‐III by both a functional assay and an immunologic assay demonstrated a rapid decrease in serum AT‐III levels, followed by a protracted recovery beyond the period of ...
N, Anderson, J J, Lokich, J L, Tullis
openaire   +2 more sources

Evidence-based medicine III: level of evidence

Journal of Pediatric Urology, 2019
The present article is the third installment in a five-part series related to evidence-based medicine (EBM) provided by the European Society for Paediatric Urology Research Committee. It will present the different levels of evidence (i.e. systematic review, randomized controlled trial, cohort study) available to clinicians and researchers and describe ...
M. Kaefer   +7 more
openaire   +4 more sources

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