Results 251 to 260 of about 24,063,572 (372)

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Relationship between the carrying angle, medial instability of the elbow, and general joint laxity in high school baseball pitchers: a cross-sectional study

JSES International
Background: An increase in carrying angle (CA) on the throwing side has been reported in professional baseball pitchers. However, no reports have investigated high school baseball pitchers, and the associated factors remain unknown.
Koichiro Yanai, MD, Tsuyoshi Tajika, MD, PhD, Yuhei Hatori, MD, Fukuhisa Ino, MD, Ryosuke Miyamoto, MD, Masataka Kamiyama, MD, Noritaka Hamano, MD, PhD, Tsuyoshi Sasaki, MD, PhD, Hitoshi Shitara, MD, PhD, Kenji Takagishi, MD, PhD, Hirotaka Chikuda, MD, PhD   +10 more
doaj  

Serum FDP levels in decompensated liver cirrhosis with special reference to those of HPT, PT, AT-III and PA.

, 1985
Toshifumi KASHIWABARA, Yasuhiro Takikawa, Akihiko Murakami, Toshimi Yoshida, Kazuyuki Suzuki, Shunichi Sato   +5 more
openalex   +2 more sources

Neonatal resuscitation program (NRP) guidelines and timing of major resuscitation events in delivery rooms at a level III NICU: Understanding deviations. [PDF]

Resusc Plus
Boddu PK, Velumula PK, Jani S, Fernandes N, Lua J, Natarajan G, Bajaj M, Thomas R, Chawla S.   +8 more
europepmc   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Interaction of Alkylmercuric Compounds with Sodium Selenite. III. Biotransformation, Levels of Metallothioneinlike Proteins and Endogenous Copper in Some Tissues of Rats Exposed to Methyl or Ethylmercuric Chloride with and without Sodium Selenite

, 1985
Elzbieta A. Brzeznicka, Jadwiga Chmielnicka   +1 more
openalex   +1 more source

3‐Hydroxy‐3‐methylglutaryl CoA reductase inhibitors reduce serum triglyceride levels through modulation of apolipoprotein C‐III and lipoprotein lipase [PDF]

, 1999
Kristina Schoonjans, Julia Peinado‐Onsurbe, Jean‐Charles Fruchart, Anne Tailleux, Catherine Fiévet, Johan Auwerx   +5 more
openalex   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Decreased carbonic anhydrase III levels in the liver of the mouse mutant ‘toxic milk’ (tx) due to copper accumulation [PDF]

, 1997
Andrew Grimes, Jennifer A. Paynter, Ian D. Walker, Mrinal Bhave, Julian F. B. Mercer   +4 more
openalex   +1 more source

Is a level III dissection necessary for a positive sentinel lymph node in melanoma?

Journal of Surgical Oncology, 2012
J. Namm, Alfred E. Chang, V. Cimmino, R. Rees, T. Johnson, M. Sabel   +5 more
semanticscholar   +1 more source