Results 51 to 60 of about 73,791 (253)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Non-Suicidal Self-Injury across the Levels of Personality Functioning among Mental Health Help-Seeking Adolescents

Psichologija
Non-suicidal self-injury (NSSI) is highly prevalent among adolescents receiving mental health services; it has been increasingly linked to impairments in personality development.
Agnė Grigaitė, Emilija Grikšelytė, Elena Gaudiešiūtė, Rasa Barkauskienė   +3 more
doaj   +1 more source

Relationship Between Personality Disorders Scales, Pathological Personality Traits, and Six Domains of Functioning in Sample With Alcohol Use Disorder

Frontiers in Psychiatry, 2020
BackgroundStudies reveal a functional impairment in patients with personality disorders (PDs), but there is not enough information to form conclusions about this relation in patients with alcohol use disorder (AUD).
Jeļena Koļesņikova, Viktorija Perepjolkina, Velga Sudraba, Kristīne Mārtinsone, Ainārs Stepens   +4 more
doaj   +1 more source

Levels of Personality Functioning Scale Self-Report Validation Journal of Personality Assessment

, 2017
Validation of the Levels of Personality Functioning Scale - Self-Report. Results suggest that the measure has a robust single dimension and that it correlates in a very general manner with a wide range of maladaptive personality variables, consistent with its purpose as a measure of non-specific personality pathology.
Good, Evan, Morey, Leslie, Hopwood, Christopher   +2 more
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Risk Factors for Adult Depression: Adverse Childhood Experiences and Personality Functioning

Frontiers in Psychology, 2020
Background: Depressive disorder is one of the main health problems worldwide. Many risk factors have been associated with this pathology. However, while the association between risks factors and adult depression is well established, the mechanisms behind
Paula Dagnino, Paula Dagnino, Paula Dagnino, María José Ugarte, Felipe Morales, Sofia González, Daniela Saralegui, Johannes C. Ehrenthal   +7 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Measurement invariance and validation of the LPFS-BF 2.0 in clinical and community samples of Turkish adolescents

BMC Psychology
Background Given the limited number of validation studies on the LPFS-BF 2.0 in adolescents and scarce test–retest data, the current study aimed to examine the psychometric properties of the Turkish version of the LPFS-BF 2.0 in adolescents.
Fatma Coşkun, Ömer Faruk Akça, Ayhan Bilgiç, Carla Sharp, Joost Hutsebaut   +4 more
doaj   +1 more source

What influences treatment satisfaction in patients with personality disorders? A naturalistic investigation in a hospitalization setting

Mental Illness, 2016
Treatment satisfaction of different mental disorders is still poorly understood, but of high clinical interest. Inpatients of a general psychiatric care hospital were asked to fill out questionnaires on satisfaction at discharge and clinical variables at
Stefan Gebhardt, Martin Tobias Huber
doaj   +1 more source