Results 91 to 100 of about 169,732,242 (309)

Service level agreements in grids

, 2009
From 22.03. to 27.03.09, the Dagstuhl Seminar 09131 "Service Level Agreements in Grids" was held in Schloss Dagstuhl, Leib- niz Center for Informatics. During the seminar, several participants pre- sented their current research, and ongoing work and open

core   +1 more source

09131 Executive Summary – Service Level Agreements in Grids [PDF]

, 2009
Grid computing allows virtual organizations to share resources across administrative domains. In its early days, Grid computing was inspired by the need for transparent access to supercomputing resources and by the idea to even couple the resources in a ...
Gerndt, Hans Michael, Ziegler, Wolfgang, Rana, Omer F., von Laszewski, Gregor   +3 more
core   +1 more source

Comprehensive assessment of side friction impacts on capacity and level of service under urban heterogeneous traffic conditions

Frontiers in Built Environment
Indian cities are experiencing an unprecedented growth in the number of vehicles on the road, resulting in a surge in traffic accidents, delays, pollution, congestion, and unequal access to transportation.
S. Vasantha Kumar, Shishodiya Ghanshyam Singh   +1 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Empirical-Data-Driven LOS Reclassification via Adaptive Branching Framework for Reflecting Urban Traffic Heterogeneity

Applied Sciences
Conventional standards for evaluating the Korean Highway Capacity Manual (HCM) and U.S. HCM often inadequately represent the localized macroscopic traffic dynamics inherent in complex urban networks.
Yechan Jeong, Hyejong Ha, Jinsook Jeon, Youngtae Son, Jaehee Jung   +4 more
doaj   +1 more source

Manufacturer invasion and online sales mode strategy considering the level of service quality. [PDF]

PLoS One, 2023
Zhang G, Liu X, Su G.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Business model driven service architecture design for enterprise application integration [PDF]

, 2008
Increasingly, organisations are using Service-Oriented Architecture (SOA) as an approach to Enterprise Application Integration (EAI), which is required for the automation of business processes.
Pahl, Claus, Gacitua-Decar, Veronica
core   +3 more sources

Bi-objective evolutionary optimization of level of service in urban transportation based on traffic density

Cogent Engineering, 2018
This work investigates levels of service in urban transportation coupling a multi-objective evolutionary algorithm with the multi-agent traffic simulator MATSim.
Rolando Armas, Hernán Aguirre, Kiyoshi Tanaka   +2 more
doaj   +1 more source