Results 101 to 110 of about 1,407,119 (265)

The Use of Multimodal Service Level and Artificial Neural Networks for the Improvement of Public Transport

Romanian Journal of Transport Infrastructure
Most of the major modern cities of the world face problems due to traffic conditions. However, in the last decade the degree of motorization combined with increased urbanization and population density causes excess traffic capacity during peak hours on ...
Maleanu Mihai, Ungureanu Valentin-Vasile
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Improving the Capacity of the Carriageway of the City Streets of Karbala

RUDN Journal of Engineering Research
The religious and economic importance of the city of Karbala led to an increase in the number of daily trips and an increase in the flow of traffic, therefore it was necessary to know the city’s road network.
Hayder S. Khudhair, Hamid A.E. Al-Jameel, Vladimir N. Konoplev, Artur R. Asoyan   +3 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

An Experimental Pilot Approach to Evaluate the Infrastructure Accessibility and Level of Service at Metro Station Platforms

Applied Sciences
Metro stations are essential for daily commuting, but overcrowding due to increased demand can severely impact infrastructure quality and passenger experience.
Sebastian Seriani, Vicente Aprigliano, Alvaro Peña, Shirley Gonzalez, Bernardo Arredondo, Iván Bastías, Emilio Bustos, Jose Requesens, Ariel Lopez, Taku Fujiyama   +9 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Determining the Optimal Level of Service of the Airport Passenger Terminal for Low-Cost Carriers Using the Analytical Hierarchy Process

Applied Sciences
Based on the projected growth in passenger air traffic and the need for better utilization of existing capacities, the level of service (LOS) concept in the design and planning of airport terminal facilities is crucial.
Jelena Pivac, Igor Štimac, Dajana Bartulović, Andrija Vidović   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

AsyncSLA: Towards a Service Level Agreement for Asynchronous Services

Proceedings of the 39th ACM/SIGAPP Symposium on Applied Computing
The research described in this paper has been partially supported by the AIDOaRT and TRANSACT projects, which have received funding from the ECSEL Joint Undertaking (JU) under grant agreement No. 101007350 and 101007260 respectively. The JU receives support from the European Union’s Horizon 2020 research and innovation programme and Sweden, Austria ...
Oriol, Marc, Gómez, Abel, Cabot, Jordi
openaire   +2 more sources