Results 171 to 180 of about 62,644 (199)
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
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Separating disconnected quadratic level sets by other quadratic level sets
Journal of Global Optimization, 2023zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Huu-Quang Nguyen +2 more
openaire +1 more source
The American Mathematical Monthly, 2014
We prove that every continuous function from a disk to the real line has a level set containing a connected component of diameter at least .
Aleksander Maliszewski +1 more
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We prove that every continuous function from a disk to the real line has a level set containing a connected component of diameter at least .
Aleksander Maliszewski +1 more
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Setting euthanasia on the level
The Liverpool Law Review, 1993The House of Lords recently set up a Select Committee on Medical Ethics to consider euthanasia and related medical decisions at the end of life. This followed widespread publicity surrounding recent cases, particular the trial and conviction of a doctor for the attempted murder of a consenting terminally ill patient, and the House of Lords' ruling that
Tim, Helme, Nicola, Padfield
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2010
We define the robustness of a level set homology class of a function f : X → R as the magnitude of a perturbation necessary to kill the class. Casting this notion into a group theoretic framework, we compute the robustness for each class, using a connection to extended persistent homology.
Paul Bendich +3 more
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We define the robustness of a level set homology class of a function f : X → R as the magnitude of a perturbation necessary to kill the class. Casting this notion into a group theoretic framework, we compute the robustness for each class, using a connection to extended persistent homology.
Paul Bendich +3 more
openaire +1 more source
Journal of Cybernetics, 1977
Abstract In practical applications of fuzzy set theory, e.g., in pattern recognition, information retrieval, etc., the reader is not advised-for the reasons of the amount of the considered object universal set and the capacity of computer memory involved-to consider fuzzy sets defined in the whole universal set, when it is sufficient-from the point of ...
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Abstract In practical applications of fuzzy set theory, e.g., in pattern recognition, information retrieval, etc., the reader is not advised-for the reasons of the amount of the considered object universal set and the capacity of computer memory involved-to consider fuzzy sets defined in the whole universal set, when it is sufficient-from the point of ...
openaire +2 more sources
Neuron segmentation with level sets
2013 Asilomar Conference on Signals, Systems and Computers, 2013We propose a variational scheme for neuron segmentation. The growing demand for an automated image analysis tool for efficient segmentation of neurites has led to significant focus and advancement in the field of neuro-image analysis. However, the complex structure of the neurites and imaging artifacts pose considerable challenge for automated image ...
Suvadip Mukherjee +2 more
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Level set estimation on the sphere
2010 IEEE International Conference on Acoustics, Speech and Signal Processing, 2010We investigate a technique for estimating level sets of functionals on the 2-sphere. The surface of the sphere is finely partitioned using a tree decomposition and a candidate level set is obtained by minimizing a regularized cost on the tree. A cycle spinning scheme, implemented as an ensemble classification method, is developed to decrease the ...
Alexander Lorbert, Peter J. Ramadge
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