Results 151 to 160 of about 4,243,261 (296)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Level-set shape optimization via polytopic discontinuous Galerkin methods

open access: yes
We introduce a new level-set shape optimization approach based on polytopic (i.e.,polygonal in two and polyhedral in three spatial dimensions) discontinuous Galerkin methods.
Raphael S Fernandes (22008956)   +2 more
core  

Evaluation of Lipid Profile in Patients with Cardiovascular Diseases Receiving Simvastatin in Palu Indonesia

open access: yes, 2018
Cardiovascular diseases (CVDs) are the leading cause of death worldwide which results from the impaired function of the heart and blood vessels. The most common CVDs are coronary heart and stroke.
Faraditha Amalia   +3 more
core   +1 more source

Leveled partially ordered sets

open access: yesComputational and Applied Mathematics
Abstract This article presents our approach to modeling a problem posed by a company aiming to optimize the 3D printing of an object within the context of additive manufacturing, where each object is created layer by layer. We introduce the concept of leveled partially ordered sets to manage large sets of points that represent each layer of ...
Fernando Fueyo   +5 more
openaire   +4 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The Possibility of Using Allelic Variants of Electrophoretic Spectra of Storage Proteins in the Breeding of Sunflower

open access: yes
Relevance of the provided research work lies in the need to create parental lines of sunflower with high genetic purity, high combinatorial ability to obtain modern hybrids capable of forming a high level of yield in the arid conditions of the Steppe of ...
Aksyonov, Igor
core   +1 more source

Change of 2H/1H Ratio and Adaptive Potential in Living Systems under Formation of Isotope Gradient

open access: yes, 2019
This article presents data on ability of drinking water with depleted concentrations of deuterium (deuterim depleted water – DDW, ?2H = -762 ‰) to influence on the adaptive capacities and functional activity of rats organism during long period of DDW ...
L.V. Fedulova   +3 more
core   +1 more source

Level-set based adaptive-active contour segmentation technique with long short-term memory for diabetic retinopathy classification. [PDF]

open access: yesFront Bioeng Biotechnol, 2023
Bhansali A   +5 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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