Results 191 to 200 of about 34,849,215 (311)

Level Set Image Feature Detection and Application in COVID-19 Image Feature Knowledge Detection.

Biomed Res Int, 2023
Ji D, Liu Y, Zhang Q, Zheng W.
europepmc   +1 more source

A level set approach to high fidelity interactive bone shaving for virtual training of surgical osteotomies. [PDF]

Proc SPIE Int Soc Opt Eng, 2022
Wilson A, Scheirich H, Paniagua B, White R, Nguyen T, Arikatla V.   +5 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

A novel method for evaluating and visualizing scratch wound healing assays using level-set and image sector analysis. [PDF]

PNAS Nexus
Vašinková M, Krumnikl M, Gharibian A, Mičulek O, Kriegová E, Gajdoš P.   +5 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Inverse-design topology optimization of magnonic devices using level-set method. [PDF]

Npj Spintron
Voronov AA, Cuervo Santos M, Bruckner F, Suess D, Chumak AV, Abert C.   +5 more
europepmc   +1 more source

A weighted region-based level set method for image segmentation with intensity inhomogeneity. [PDF]

PLoS One, 2021
Yu H, Sun P, He F, Hu Z.
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Enhanced medical image segmentation using novel level set evolution and efficient optimization. [PDF]

Sci Rep
Wali S, Jhangeer A, Rahimzai AA, Samina S, Imran M.   +4 more
europepmc   +1 more source

LSM-SEC: Tongue Segmentation by the Level Set Model with Symmetry and Edge Constraints. [PDF]

Comput Intell Neurosci, 2021
Gao S, Guo N, Mao D.
europepmc   +1 more source