Results 101 to 110 of about 5,094,747 (280)

Solving the Variational Inequality Problem Defined on Intersection of Finite Level Sets

Abstract and Applied Analysis, 2013
Consider the variational inequality VI(C,F) of finding a point x*∈C satisfying the property 〈Fx*,x-x*〉≥0, for all x∈C, where C is the intersection of finite level sets of convex functions defined on a real Hilbert space H and F:H→H is an L-Lipschitzian ...
Songnian He, Caiping Yang
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

FOUR NEW OPERATORS OVER THE GENERALIZED INTUITIONISTIC FUZZY SETS

Journal of New Theory, 2017
– In this paper, newly defined four level operators over generalized intuitionistic fuzzy sets (GIFSBs) are proposed. Some of the basic properties of the new operators are discussed.
Ezzatallah Baloui Jamkhaneh, Asghar Nadi Ghara   +1 more
doaj  

Computation of Ice Shedding Trajectories Using Cartesian Grids, Penalization, and Level Sets

Modelling and Simulation in Engineering, 2011
We propose to model ice shedding trajectories by an innovative paradigm that is based on cartesian grids, penalization and level sets. The use of cartesian grids bypasses the meshing issue, and penalization is an efficient alternative to explicitly ...
Héloïse Beaugendre, François Morency, Federico Gallizio, Sophie Laurens   +3 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Confidence sets for a level set in linear regression

Statistics in Medicine
Regression modeling is the workhorse of statistics and there is a vast literature on estimation of the regression function. It has been realized in recent years that in regression analysis the ultimate aim may be the estimation of a level set of the regression function, ie, the set of covariate values for which the regression function exceeds a ...
Fang Wan, Wei Liu, Frank Bretz
openaire   +4 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

On space-time quasiconcave solutions of the heat equation

, 2019
In this paper we first obtain a constant rank theorem for the second fundamental form of the space-time level sets of a space-time quasiconcave solution of the heat equation.
Chen, Chuanqiang, Ma, Xinan, Salani, Paolo   +2 more
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source