Results 131 to 140 of about 9,835,184 (256)
Myyjä myyntiprosessin kehittäjänä : case: SHIFT Events Oy [PDF]
, 2019 Tässä opinnäytetyössä selvitetään ja analysoidaan SHIFT Events Oy:n myyntiprosessia ja annetaan siihen kehitysehdotuksia, jotka pyrkivät selkeyttämään ja tehostamaan asiakkaisiin kohdistuvia myyntitoimenpiteitä yksittäisen myyjän näkökulmasta ...
Virtanen, Veli-Pekka
core
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Communications PhysicsUnderstanding how charge carriers behave in semiconductors is key to improving next-generation optoelectronic devices. Here we introduce an advanced space-charge-limited current model that enables detailed extraction of mobility, charge carrier ...
Stevan Gavranovic +3 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Texas Low-Level Radioactive Waste Transportation Cost Evaluation, December 1983
, 1983 Report of the design of a low-level radioactive waste disposal facility and summarized information relating to the costs it would/does ...
Texas Low-Level Radioactive Waste Disposal Authority
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
THE RELATIONSHIP BETWEEN WORK SHIFT WITH WORK STRESS AND NURSES’ ABSENTEEISM
The International Journal of Humanities Technology and Civilization, 2019 This study aims to determine the differences in the level of work stress and nurse absenteeism on each shift and the relationship between work stress and the nurse's attendance rate in each hospital and to find the difference between the two hospitals ...
Yusrizal Ibrahim
doaj