Results 41 to 50 of about 548,200 (260)

Why Does Bad News Increase Volatility and Decrease Leverage? [PDF]

open access: yes
A recent literature shows how an increase in volatility reduces leverage. However, in order to explain pro-cyclical leverage it assumes that bad news increases volatility, that is, it assumes an inverse relationship between first and second moments of ...
Ana Fostel, John Geanakoplos
core   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Bank Capital Structure and Procyclicality of Leverage

open access: yes, 2019
This book investigates the determinants of bank capital structure and procyclical behavior of leverage. A panel data analysis is developed to find out the relation between different types of leverage ratios and asset growth of banks.

core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Leverage and firm performance: Empirical evidence from Indian food processing industry [PDF]

open access: yesManagement Science Letters, 2019
The current study examines the association between financial performance and leverage for 56 food processing firms listed in BSE over the period 2000-2018 using pooled OLS, fixed effects, and random effects models.
Sasikanta Tripathy, Abdul Rahman Shaik
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Bureaucratic access points and leverage [PDF]

open access: yes, 2013
textThis project studies how bureaucratic behavior influences policy implementation. It presents a novel bureaucratic access points and leverage theory, which help us understand how policies are successfully implemented in the midst of bureaucratic ...
Sternemann, Daniel Thomas
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Determinants of behaviour of working capital requirements of BSE listed companies: An empirical study using co-integration techniques and generalised method of moments

open access: yesCogent Economics & Finance, 2020
The paper investigates the determinants of working capital to forecast the future requirement of working capital of BSE-listed top 150 companies in India.
Rakesh Kumar Sharma   +2 more
doaj   +1 more source

The capital structure of agricultural enterprises in the Visegrad countries

open access: yesAgricultural Economics (AGRICECON), 2020
The Visegrad countries - or the V-4 countries: the Czech Republic, Hungary, Poland and Slovakia - is strong regional cooperation of four EU member states in Eastern-Central-Europe aimed at strengthening the positions of the members on both a European and
Veronika Fenyves   +3 more
doaj   +1 more source

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