Results 101 to 110 of about 744,108 (349)

Leveraging the persistent radical effect in the synthesis of trans-2,3-diaryl-dihydrobenzofurans [PDF]

open access: gold, 2022
Bec J. Roldan   +5 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

The Effect of Product Market Competition on Capital Structure: Empirical Evidence from the Newspaper Industry [PDF]

open access: yes
This paper analyzes whether the extent of product market competition that a firm faces affects its capital structure. We study the effect of competition on leverage for firms acting in the US newspaper industry.
Ernesto Schargrodsky
core  

The Due diligence system in the EU’s Timber Regulation: non-tariff trade barrier or leverage effect? [PDF]

open access: yes, 2016
This paper presents a novel spatial equilibrium model to analyse the leverage impact of the EU’s Timber Regulation on sustainable timber production. This leverage effect is an argument in favour of FLEGT but it has never been investigated thoroughly, or ...
Brusselaers, Jan, Buysse, Jeroen
core  

Spatial and temporal structures of four financial markets in Greater China

open access: yes, 2014
We investigate the spatial and temporal structures of four financial markets in Greater China. In particular, we uncover different characteristics of the four markets by analyzing the sector and subsector structures which are detected through the random ...
Jiang, X. F., Ouyang, F. Y., Zheng, B.
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Capital Structure and Regulation: Does Ownership Matter? [PDF]

open access: yes
We construct a comprehensive panel data of 96 publicly traded European utilities over the period 1994-2005 in order to study the relationship between the capital structure of regulated firms, regulated prices, and investments, and examine if and how this
Bernardo Bortolotti   +3 more
core  

GARCH models with leverage effect : differences and similarities [PDF]

open access: yes, 2009
In this paper, we compare the statistical properties of some of the most popular GARCH models with leverage e?ect when their parameters satisfy the positivity, stationarity and nite fourth order moment restrictions.
Rodríguez, Mª José, Ruiz, Esther
core   +1 more source

Principal Regression Analysis and the index leverage effect

open access: yes, 2011
We revisit the index leverage effect, that can be decomposed into a volatility effect and a correlation effect. We investigate the latter using a matrix regression analysis, that we call `Principal Regression Analysis' (PRA) and for which we provide some
Bekaert   +20 more
core   +1 more source

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