Results 111 to 120 of about 5,366 (262)
Antihistamines in pediatric allergy [PDF]
Histamine is a key mediator in allergic diseases, where it exerts most of its effects through the H1 receptor and to a less extent the H2 receptor. H1-antihistamines provide rapid relief of many of the allergic symptoms and are considered the main stay ...
El-Ghoneimy, Dalia H
core +2 more sources
Dementia and epilepsy following COVID‐19 infection in a 25‐year‐old female: A case report
Magnetic resonance imaging of the brain with contrast showing mild cerebral atrophy with the widening of sulci in both the cerebral hemispheres and mild dilatation of the supratentorial ventricular system. Key Clinical Message Significant atypical neurologic signs have also been recorded in COVID‐19 individuals, along with a variety of other extra ...
Farea Ahmed+5 more
wiley +1 more source
Possible Applications of Levocetirizine in the Treatment of Bronchitis and Pneumonia in Children with Atopic ...
Yu.V. Marushko, G.G. Shef
doaj +1 more source
Abstract Chronic urticaria (CU) is a mast cell (MC)‐dependent disease with limited therapeutic options. Current management strategies are directed at inhibiting IgE‐mediated activation of MCs and antagonizing effects of released mediators. Due to the complexity and heterogeneity of CU and other MC diseases and mechanisms of MC activation—including ...
Martin Metz+7 more
wiley +1 more source
Persistent Allergic Rhinitis and the XPERT Study
Allergic rhinitis (AR) is a chronic disease with an increasing trend in most of the Western Countries. It may significantly impair the individual quality of life (QoL) and also represents a social burden for its economic costs. Levocetirizine (XYZAL; UCB
Anthi Rogkakou, MD+3 more
doaj
Cost-analysis study of second generation antihistamines used in the treatment of allergic rhinitis in India [PDF]
Background: Second-generation antihistamines (SGAs) are the most commonly used drugs for AR nowadays. The cost of medicines is very important determinant in drug compliance; selection of low cost quality drugs would thus be helpful in improving ...
Kumar, Hitender, Singh, Amandeep
core +2 more sources
Efficacy of L-cet Use in Children with Seasonal Allergic Rhinitis
The paper presents the study data on clinical efficacy of antihistamine syrup L-cet in children with seasonal allergic rhinitis. Received data show high therapeutic efficacy and good tolerability of the drug in children.
Yu.G. Antypkin+3 more
doaj +1 more source
Yu Cheng,1 Bi-Juan Lin,1 Jin-Hua Guo,1 Bing-Lin Huang,1 Lin-Ping Fang,1 Wan-Cai Que,1 Mao-Bai Liu,1 Xin-Feng Chen,1 Hong-Qiang Qiu1,2 1Department of Pharmacy, Fujian Medical University Union Hospital, Fuzhou 350001, People’s Republic of China ...
Cheng Y+8 more
doaj
Pharmacology of antihistamines
H 1- antihistamines, the mainstay of treatment for urticaria, were developed from anticholinergic drugs more than 70 years ago. They act as inverse agonists rather than antagonists of histamine H 1 -receptors which are members of the G-protein family ...
Martin K Church, Diana S Church
doaj +1 more source
Probe dependency in the determination of ligand binding kinetics at a prototypical G protein-coupled receptor [PDF]
© 2019, The Author(s). Drug-target binding kinetics are suggested to be important parameters for the prediction of in vivo drug-efficacy. For G protein-coupled receptors (GPCRs), the binding kinetics of ligands are typically determined using association ...
Bosma, Reggie+12 more
core +3 more sources