The Effects of Cetirizine on P-glycoprotein Expression and Function In vitro and In situ [PDF]
Advanced Pharmaceutical Bulletin, 2016 Purpose: P-glycoprotein (P-gp) plays a major role in oral absorption of drugs. Induction or inhibition of P-gp by drugs contributes to variability of its transport activity and often results in clinically relevant drug-drug interactions.
Mehran Mesgari Abbasi +4 more
doaj +3 more sources
Adsorption Characteristics of Cetirizine on Graphene Oxide
Sustainable Chemistry, 2023 Water pollution caused by emerging contaminants such as pharmaceutical compounds is a growing problem worldwide. In this reported work, graphene oxide (GO) was directly used to remove an antihistamine drug, cetirizine. GO was prepared from graphite using
Tuhin Bhattacharjee +5 more
doaj +2 more sources
Cetirizine per os: exposure and antihistamine effect in the dog
Acta Veterinaria Scandinavica, 2018 Background Cetirizine is an antihistamine used in dogs, but plasma concentrations in relation to effect after oral administration are not well studied.
Carl Ekstrand +4 more
doaj +2 more sources
Cetirizine suppresses cancer-associated fibroblast-mediated fibrotic remodeling and epithelial–mesenchymal transition via histamine H1 receptor inverse agonism [PDF]
Breast Cancer ResearchBackground Triple-negative breast cancer (TNBC) is an aggressive subtype characterized by high metastatic potential and limited therapeutic options.
Aya Sasaki +12 more
doaj +2 more sources
Gender and age variations in neuropsychiatric adverse events of cetirizine and levocetirizine: a disproportionality analysis of ICSRs from FAERS and EudraVigilance data [PDF]
Frontiers in PharmacologyBackgroundThis study analyzed neuropsychiatric adverse drug events (ADEs) associated with cetirizine and levocetirizine using data from the FDA Adverse Event Reporting System (FAERS) and EudraVigilance databases to inform safer clinical use for different
Tingting Yang +9 more
doaj +2 more sources
Unexpected Fetal Supraventricular Tachycardia Temporally Associated With Maternal Antihistamine Use: A Case Report [PDF]
Case Reports in Obstetrics and GynecologyFetal supraventricular tachycardia (SVT) represents the most common cause of sustained fetal tachyarrhythmia and may result in significant hemodynamic compromise when persistent.
Khadijeh Riazi Kermani +3 more
doaj +2 more sources
Perspectives in Clinical Research, 2023 Purpose: Bilastine is a novel second-generation antihistaminic. Very few studies in Indian population have compared the safety and efficacy of bilastine with other second-generation antihistaminic like cetirizine.
Vishakha V Sinha +4 more
doaj +1 more source
Chronic ingestion of H1-antihistamines increase progression of atherosclerosis in apolipoprotein E-/- mice. [PDF]
PLoS ONE, 2014 Although increased serum histamine levels and H1R expression in the plaque are seen in atherosclerosis, it is not known whether H1R activation is a causative factor in the development of the disease, or is a host defense response to atherogenic signals ...
Vineesh V Raveendran +8 more
doaj +1 more source
A Rare Adverse Effect of Cetirizine in a 7- Month-Old Infant: Dystonic Reaction
Çocuk Dergisi, 2021 Cetirizine is a selective H1 histamine receptor antagonist derived from piperazine. Piperazine is a cyclic moiety molecule located in the structure of many drugs, including anxiolytics, antidepressants, and antipsychotics.
Ayşe Süleyman +7 more
doaj +1 more source
Journal of Pharmacy & Pharmaceutical Sciences, 2021 Purpose: Prostaglandins play a pivotal role in modulating hair growth cycle. Prostaglandin F2α and prostaglandin E have stimulating and prostaglandin D has inhibitory effects on hair follicle.
Delaram Hossein Mostafa +5 more
doaj +1 more source