Results 31 to 40 of about 8,822 (164)

Cetirizine and Levetiracetam as Inhibitors of Monoacylglycerol Lipase: Investigating Their Repurposing Potential as Novel Osteoarthritic Pain Therapies

Pharmaceuticals, 2023
Osteoarthritis is characterized by progressive articular cartilage degradation, subchondral bone changes, and synovial inflammation, and affects various joints, causing pain and disability.
Corina Andrei, Dragos Paul Mihai, Georgiana Nitulescu, Anca Ungurianu, Denisa Marilena Margina, George Mihai Nitulescu, Octavian Tudorel Olaru, Radu Mihai Busca, Anca Zanfirescu   +8 more
doaj   +1 more source

Plasma and urine pharmacokinetics of hydroxyzine and cetirizine following repeated oral administrations to exercised horses [PDF]

, 2022
Hydroxyzine and cetirizine are first- and second-generation oral antihistamine drugs, respectively, used to treat allergic reactions in horses. Cetirizine is also a metabolite of hydroxyzine, which may lead to complexities in regulating their use in ...
Aldurdunji, Mohammed, Stuart W. Paine, Alix Garth‐Greeves, Pamela R. Hincks, Hincks, Pamela R., Muir, Tessa, Paine, Stuart W., Garth-Greeves, Alix, Tessa Muir, Mohammed Aldurdunji   +9 more
core   +1 more source

Cetirizine-induced fixed drug eruption

, 2018
Cetirizine, a piperazine-derivative second-generation antihistaminic, is used for a wide variety of disorders such as urticaria, eczema, and allergies. Adverse reactions due to this drug are usually rare, especially fixed drug eruption (FDE), a delayed ...
Sakthibalan Murugesan, Gerard Marshall Raj, Mangaiarkkarasi Adhimoolam, Selvalaxmi Gnanasegaran, Srija Gopal   +4 more
core   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

High‐risks drug adverse events associated with Cetirizine and Loratadine for the treatment of allergic diseases: A retrospective pharmacovigilance study based on the FDA adverse event reporting system database

Clinical and Translational Allergy
Background Cetirizine and Loratadine are the two best‐selling second‐generation antihistamines for allergic diseases. This study aims to provide a comparative analysis of the differences in adverse drug events (ADEs) between these two medications, which ...
Weili Kong, Yijun Dong, Sixi Yi, Wei Mo, Hui Yang   +4 more
doaj   +1 more source

Suppression of wheal and flare in histamine test by the main H1 antihistamines commercialized in Brazil [PDF]

Anais Brasileiros de Dermatologia, 2018
: Background: Several dermatoses are mediated by histamine, such as urticaria, angioedema, and papular urticaria. There are no Brazilian studies comparing the potency of antihistamines.
Helena Maciel-Guerra, Mariana Álvares Penha, Marília Formentini Scotton Jorge, Ricardo da Silva Libório, Ana Cláudia Nazareno dos Anjos Carrijo, Maria Rita Parise-Fortes, Hélio Amante Miot   +6 more
doaj   +2 more sources

Successful Treatment of Refractory Lichen Amyloidosus With Dupilumab

JEADV Clinical Practice, EarlyView.
ABSTRACT Lichen amyloidosis (LA) is a chronic, pruritic dermatosis with papillary dermal amyloid deposition. Standard therapies often fail, and most reports of dupilumab in LA involve patients with concomitant atopic dermatitis. We report a 32‐year‐old man with refractory, non‐atopic LA who had failed topical corticosteroids, tacrolimus, phototherapy ...
Sohrab Elahwiesy, Franziska Jochims, Manfred Kunz, Susann Forkel, Jan‐Christoph Simon, Benjamin Klein   +5 more
wiley   +1 more source

A comparative study of efficacy and tolerability of cetirizine and bilastine in patients of allergic rhinitis: An open-label, randomized, parallel-group study

Perspectives in Clinical Research
Purpose: Allergic rhinitis (AR) is a type 1 allergic disease of the nasal mucosa, characterized by paroxysmal repetitive sneezing, watery rhinorrhea, and nasal blockage with the prevalence of 25% worldwide.
Sneha P. Pawar, Punam A. Gosavi, Mrunalini Vinay Kalikar   +2 more
doaj   +1 more source

Safety, Efficacy, and Mechanism of Action of Budesonide in Rhinitis and Rhinosinusitis: A Systematic Review

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Budesonide is a corticosteroid with unique pharmacokinetic and pharmacodynamic properties that has been a frontline treatment for patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS) since the 1990s. As research on budesonide continues to produce new insights, our aim was to synthesize recent investigations and ...
David W. Kennedy, Lei Cheng, De‐Yun Wang   +2 more
wiley   +1 more source

Cetirizine: A New and Effective Corrosion Inhibitor for Mild Steel in 1 M HCl solution

International Journal of Electrochemical Science, 2012
Cetirizine was investigated as corrosion inhibitor for mild steel (MS) in 1 M HCl solution by weight loss, electrochemical measurements and quantum chemical calculations.
Priyanka Singh, Ambrish Singh, M.A. Quraishi, Eno E. Ebenso   +3 more
doaj   +1 more source