Results 231 to 240 of about 5,366 (262)
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Current Medicinal Chemistry, 2006
Histamine plays a prominent and diverse role in the pathophysiology of allergic disease and therapeutic intervention is therefore typically focused on blocking the effects of this biogenic amine. A new antihistamine, levocetirizine, is the R-enantiomer of cetirizine dihydrochloride and like its parent compound undergoes minimal hepatic metabolism ...
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Histamine plays a prominent and diverse role in the pathophysiology of allergic disease and therapeutic intervention is therefore typically focused on blocking the effects of this biogenic amine. A new antihistamine, levocetirizine, is the R-enantiomer of cetirizine dihydrochloride and like its parent compound undergoes minimal hepatic metabolism ...
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Analytical Methods
Levocetirizine is one of the widely used antihistamines and has the potential to form N-nitrosopiperazine (NPZ) during drug synthesis, manufacturing, or storage.
Yujin Lim+3 more
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Levocetirizine is one of the widely used antihistamines and has the potential to form N-nitrosopiperazine (NPZ) during drug synthesis, manufacturing, or storage.
Yujin Lim+3 more
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Comparative Analysis of Four Brands of Levocetirizine Tablets Available in Karachi, Pakistan
International Journal of Trends in Pharmaceutical and Chemical Research, 2023The basic purpose to prepare any drug is to increase quality of life; therefore, different quality control tests have been performed to achieve the desired outcome. One of the most frequently used dosage form is tablet which requires different techniques
Atiya Tabassum+5 more
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Pharmacokinetic evaluation of levocetirizine
Expert Opinion on Drug Metabolism & Toxicology, 2011There have recently been guidelines developed for the diagnosis and treatment of rhinitis and urticaria. For both conditions, second-generation antihistamines remain as the first-line therapy.The article presents the current pharmacology, chemical properties, pharmacokinetics and metabolism of levocetirizine.
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Expert Review of Clinical Pharmacology
Introduction Chronic spontaneous urticaria (CSU) is characterized by urticaria persisting for more than 6 weeks. Antihistamines, notably sgAH (second generation antihistamines) are the first line of treatment for CSU.
K. Sardana+11 more
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Introduction Chronic spontaneous urticaria (CSU) is characterized by urticaria persisting for more than 6 weeks. Antihistamines, notably sgAH (second generation antihistamines) are the first line of treatment for CSU.
K. Sardana+11 more
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Green Processing and Synthesis
The main objective of this article was to develop method and validate quaternary estimation of caffeine (CFE), paracetamol (PCM), levocetirizine (LEV), and phenylephrine (PHE) and to conduct degradation experiments using reverse-phase high-performance ...
Vineetha Rosireddy, Manikandan Krishnan
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The main objective of this article was to develop method and validate quaternary estimation of caffeine (CFE), paracetamol (PCM), levocetirizine (LEV), and phenylephrine (PHE) and to conduct degradation experiments using reverse-phase high-performance ...
Vineetha Rosireddy, Manikandan Krishnan
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Levocetirizine and cytokine production and apoptosis of human eosinophils
Allergy and Asthma Proceedings, 2007Antihistamines are a common therapy for allergic symptoms. Eosinophilic infiltration is considered a hallmark of allergic inflammation. Eosinophils are capable of mediating airway mucosal damage by producing various inflammatory mediators including cytokines, chemokines, basic granule proteins, lipid mediators, and growth factors.
Mirkka Janka-Junttila+3 more
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A treatment for allergic rhinitis:a view on the role of levocetirizine
Current Medical Research and Opinion, 2005Allergic rhinitis is a significant public health concern in many developed countries. However, despite evidence for a significant impact on patients' quality of life (QoL) including sleep disruption and reduced daytime performance, allergic rhinitis remains under-managed and hence poorly controlled. This is largely owing to lack of knowledge about, and
Holgate, Stephen+3 more
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Fixed drug eruption due to levocetirizine and cross-reactivity with cetirizine and hydroxyzine
Indian Journal of Drugs in DermatologySeveral drugs can act as possible causes for fixed drug eruptions (FDEs). The newer generation of antihistamines is considered safer and less prone to causing adverse drug reactions.
Ishan Agrawal+2 more
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International Archives of Allergy and Immunology, 2022
Introduction: Allergic rhinitis and asthma share a common inflammatory mechanism and are closely related, recognized as “one airway disease.” Thus, the guidelines recommend allergic rhinitis and asthma be treated together, and leukotriene antagonists and
Min-Hye Kim+11 more
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Introduction: Allergic rhinitis and asthma share a common inflammatory mechanism and are closely related, recognized as “one airway disease.” Thus, the guidelines recommend allergic rhinitis and asthma be treated together, and leukotriene antagonists and
Min-Hye Kim+11 more
semanticscholar +1 more source