Central Pathophysiology and Brain Network Changes Related to Camptocormia in Parkinson's Disease
ABSTRACT Background Studies on brain connectivity offer important insights into the changes that occur in central network diseases such as Parkinson's disease (PD). Camptocormia, a condition characterized by abnormal flexion of the trunk, often occurs in advanced PD, but its underlying mechanisms are not yet clear.
Tauqeer Anjum+10 more
wiley +1 more source
Rescue globus pallidus deep brain stimulation following refractory dystonia treated with subthalamic nucleus deep brain stimulation: illustrative case. [PDF]
Ambreen Y, Brandon C, Jordan Z, Dalm B.
europepmc +1 more source
Pregnenolone Reduces L‐Dopa‐Induced Dyskinesias in Female Parkinsonian Monkeys
Pregnenolone is the first neurosteroid synthesized from cholesterol in the brain. Ovariectomized female monkeys were tested as a model of women in menopause. They were lesioned with MPTP modeling Parkinson's disease and treated with levodopa (L‐dopa) to induce dyskinesias.
Mélanie Bourque+5 more
wiley +1 more source
Wearable multimodal sensing for quantifying the cardiovascular autonomic effects of levodopa in parkinsonism. [PDF]
Berkebile JA, Inan OT, Beach PA.
europepmc +1 more source
Ineffective subthalamic nucleus stimulation in levodopa-resistant postischemic parkinsonism
Paul Krack+8 more
openalex +2 more sources
Abstract Background Cognitive impairment in Parkinson's disease (PD) is a well‐established non‐motor complication that significantly affects the quality of life and well‐being of both patients and care partners. To optimally detect mild cognitive impairment or dementia, extensive neuropsychological assessment is essential.
Roberta Biundo+20 more
wiley +1 more source
Trends in Parkinson's disease medication prescribing patterns in the UK: An interrupted time series analysis (2019-2024). [PDF]
Orayj K.
europepmc +1 more source
The early treatment of Parkinson's disease: levodopa, dopamine agonists or both
M. B. Stern
openalex +1 more source
Real-World Use of COMT Inhibitors in the Management of Patients with Parkinson's Disease in Spain Who Present Early Motor Fluctuations: Interim Results from the REONPARK Study. [PDF]
López-Manzanares L+14 more
europepmc +1 more source
Reliability of Neuroimaging and Neurophysiological Tremor Features in Parkinson's Disease
Abstract Background Tremor is one of the cardinal motor symptoms of Parkinson's disease (PD). Its severity can be quantified with clinical rating scales and neurophysiology. The pathophysiology of PD tremor involves activity in the cerebello‐thalamo‐cortical circuit (CTC), which can be quantified with concurrent accelerometry‐functional magnetic ...
Luca Angelini+5 more
wiley +1 more source