Results 261 to 270 of about 100,641 (375)

Constipation Is Linked to Neuroinflammation in Early Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Constipation is a risk factor for the onset and accelerated progression of Parkinson's disease (PD), but the mechanisms underlying this association are unknown. Neuroinflammation in PD has been demonstrated in postmortem and neuroimaging studies; however, its relationship with constipation has not been investigated.
Marta Camacho   +8 more
wiley   +1 more source

Effect on Dyskinesia of the Early Combination of Amantadine to Levodopa‐Therapy in Parkinson's Disease: A Randomized, Placebo‐Controlled Study (PREMANDYSK)

open access: yesMovement Disorders, EarlyView.
Abstract Objective Investigate the efficacy of immediate‐release (IR) amantadine in reducing the risk of peak‐dose dyskinesia in early Parkinson's disease (PD) as add‐on to levodopa. Background While the use of amantadine to manage dyskinesia in PD is well supported by controlled clinical trials, data on its efficacy in patients without motor ...
Olivier Rascol   +106 more
wiley   +1 more source

Levodopa [PDF]

open access: yes, 2011
openaire   +1 more source

Bilateral Deep Brain Stimulation of the Subthalamic Nucleus or Globus Pallidus Internus Improves Gait Impairment in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background The effect of deep brain stimulation (DBS) on gait in patients with Parkinson's disease (PD) remains variable, and prospective, long‐term studies, especially involving globus pallidus interna (GPi) stimulation, are limited. Objectives We tested the hypothesis that subthalamic nucleus (STN) and GPi DBS exert acute and chronic effects
Jamal Al Ali   +14 more
wiley   +1 more source

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