Constipation Is Linked to Neuroinflammation in Early Parkinson's Disease
Abstract Background Constipation is a risk factor for the onset and accelerated progression of Parkinson's disease (PD), but the mechanisms underlying this association are unknown. Neuroinflammation in PD has been demonstrated in postmortem and neuroimaging studies; however, its relationship with constipation has not been investigated.
Marta Camacho +8 more
wiley +1 more source
Letter to the Editor Regarding 'Levodopa Intestinal Gel Infusion Therapies in Advanced Parkinson's Disease: A Swedish Study on Real-World Use and Costs'. [PDF]
Smith N.
europepmc +1 more source
Cerebral perfusion imaging predicts levodopa-induced dyskinesia in Parkinsonian rat model [PDF]
Jarrad Perron +4 more
openalex +1 more source
Response to "Letter to the Editor" Regarding Odin P, et al. 2025 'Levodopa Intestinal Gel Infusion Therapies in Advanced Parkinson's Disease: A Swedish Study on Real-World Use and Costs'. [PDF]
Taerud C.
europepmc +1 more source
AI-Driven Analysis of Wrist-Worn Sensor Data for Monitoring Individual Treatment Response and Optimizing Levodopa Dosing in Parkinson's Disease. [PDF]
Sander M +4 more
europepmc +1 more source
Abstract Objective Investigate the efficacy of immediate‐release (IR) amantadine in reducing the risk of peak‐dose dyskinesia in early Parkinson's disease (PD) as add‐on to levodopa. Background While the use of amantadine to manage dyskinesia in PD is well supported by controlled clinical trials, data on its efficacy in patients without motor ...
Olivier Rascol +106 more
wiley +1 more source
Echoes of Childhood Trauma: A Rare Case of Holmes Tremor With Neuroanatomic Imaging and Video Evidence. [PDF]
Prasad R, Gazallo D, Coni RJ.
europepmc +1 more source
Focal dystonia attributed to secondary Nigrostriatal pathway disruption following brainstem Hemorrhage: a case report. [PDF]
Zhou L, Zhao C, Sun Z, Man X, Xiang Y.
europepmc +1 more source
Abstract Background The effect of deep brain stimulation (DBS) on gait in patients with Parkinson's disease (PD) remains variable, and prospective, long‐term studies, especially involving globus pallidus interna (GPi) stimulation, are limited. Objectives We tested the hypothesis that subthalamic nucleus (STN) and GPi DBS exert acute and chronic effects
Jamal Al Ali +14 more
wiley +1 more source

