Results 281 to 290 of about 74,631 (338)

Impaired Glymphatic Clearance, Measured Using Diffusion Tensor Image Analysis Along the Perivascular Space (DTI‐ALPS), is Linked to Poor Cognitive Outcomes in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Impaired glymphatic clearance may contribute to pathological accumulations in Parkinson's (PD), but how it interacts with other processes causing dementia remains unclear. Diffusion tensor image analysis along the perivascular space (DTI‐ALPS) has been proposed as an indirect proxy for glymphatic clearance. Objectives To clarify DTI‐
Angeliki Zarkali   +8 more
wiley   +1 more source

Probabilistic Mapping of Magnetic Resonance‐Guided Focused Ultrasound (MRgFUS) Thalamotomy Targets in Essential Tremor and Tremor‐Dominant Parkinson's Disease: Insights from a German Cohort

open access: yesMovement Disorders, EarlyView.
Precise targeting in magnetic resonance‐guided focused ultrasound (MRgFUS) is critical for effective tremor control in essential tremor and tremor‐dominant Parkinson's disease, as small deviations can reduce efficacy or cause side effects. In our cohort, sweetspots were identified at Montreal Neurological Institute (MNI) coordinates x = −12.4, y = −17 ...
Jonas Krauss   +11 more
wiley   +1 more source

Electrophysiological Evidence for Impaired Central Pain Modulation in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Our study demonstrates electrophysiological evidence of impaired central pain modulation in Parkinson's disease (PD) patients using laser‐evoked potential habituation and quantitative sensory testing. PD patients exhibited reduced habituation to painful stimuli, independent of reported pain or medication.
Dilara Kersebaum   +10 more
wiley   +1 more source

Efficacy of cholinesterase inhibitors and memantine on symptoms not responsive to levodopa in patients affected by Parkinson's disease without dementia: a systematic review. [PDF]

open access: yesBMJ Neurol Open
Cani I   +11 more
europepmc   +1 more source

Comparison of Two α‐Synuclein Seed Amplification Assays for Discrimination of Parkinson Disease and Atypical Parkinsonism

open access: yesMovement Disorders, EarlyView.
Abstract Background Seed amplification assays (SAAs) for misfolded α‐synuclein (syn) have shown inconsistent results in multiple system atrophy (MSA). Objective The objective of this study was to compare a novel syn SAA (synSAA) that distinguishes between Lewy body disease (LBD) and MSA syn‐seeds (Amprion‐SAA) with an LBD‐specific synSAA (IRCCS ...
Marcello Rossi   +10 more
wiley   +1 more source

Computer vision uncovers three fundamental dimensions of levodopa-responsive motor improvement in Parkinson's disease. [PDF]

open access: yesNPJ Parkinsons Dis
Lange F   +9 more
europepmc   +1 more source

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