Results 111 to 120 of about 27,301 (241)

Clinical, Radiographic, and Histopathologic Features of Human Perigraftitis

Journal of Esthetic and Restorative Dentistry, Volume 38, Issue 7, Page 1300-1314, July 2026.
ABSTRACT Objective Perigraftitis is a biologic complication associated with dental implants placed in grafted bone, distinct from peri‐implant mucositis and peri‐implantitis. This report further characterizes its clinical, radiographic, and histopathologic features.
Jonathan H. Do, Charles M. Cobb, John T. Shen   +2 more
wiley   +1 more source

TG Nonsense Variant in Dwarf Rottweiler Dogs

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT We identified a dwarfism syndrome in six Rottweiler dogs characterized by reduced height and body weight; limb deformities, shortening of the tail and abnormally thick skin in puppies; developmental delays, pain and non‐goitrous hypothyroidism. Histological examination of the thyroid gland revealed severe chronic diffuse bilateral atrophy with
Marie Abitbol, Michaela Drögemüller, Cleo Schwarz, Etienne Furthner, Eva Dervas, Felicitas S. Boretti, Nadja S. Sieber‐Ruckstuhl, Caroline Dufaure de Citres, Chloé Pauchard, Vidhya Jagannathan, Tosso Leeb   +10 more
wiley   +1 more source

Genetically predicted hypothyroidism, thyroid hormone treatment, and the risk of cardiovascular diseases: a mendelian randomization study

BMC Cardiovascular Disorders
Background In this study, we explored the impact of hypothyroidism and thyroid hormone replacement therapy on the risk of developing cardiovascular diseases, including myocardial infarction, heart failure, and cardiac death, via Mendelian randomization ...
Shuaidan Zhang, Hangtian Yu, Yan Zhao, Angwei Gong, Chengjian Guan, Shuchen Chen, Bing Xiao, Jingchao Lu   +7 more
doaj   +1 more source

Quality by design driven RP-HPLC method optimization for analysis of levothyroxine and liothyronine in bulk and tablet dosage form

Journal of Applied Pharmaceutical Research
Background: Levothyroxine and Liothyronine are widely used in thyroid hormone replacement therapies. Simultaneously quantifying Levothyroxine and Liothyronine is important for managing thyroid hormone deficiency.
Ramdas Darade, Sanjay Pekamwar
doaj   +1 more source

From Multiple Congenital Anomalies to Pituitary Gland Malformation: Wide Spectrum of Clinical Features in a Family With FOXA2 Variant

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1452-1457, June 2026.
ABSTRACT FOXA2 (hepatocyte nuclear factor‐3β, HNF‐3β) encodes a transcriptional activator involved in early embryogenesis, particularly in the patterning and differentiation of midline structures such as the neural tube, foregut, and pituitary gland. Its role in human pathogenesis was first suspected when patients with deletion of chromosome 20p11.2 ...
Christopher Connolly, Hemant A. Parmar, Lauren Hipp, Tomoyasu Higashimoto   +3 more
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Assessing transporter‐mediated rifampin–linezolid interaction using physiologically‐based pharmacokinetic modelling

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1845-1856, June 2026.
Abstract Aims The study aims to develop a physiologically‐based pharmacokinetic (PBPK) model to quantitatively evaluate the role of ATP‐binding cassette sub‐family B member 1 (ABCB1) and ATP‐binding cassette super‐family G member 2 (ABCG2) in the drug–drug interaction (DDI) between rifampin and linezolid and to predict the impact of high‐dose rifampin ...
Hoang Dat Nguyen, Vinh Hoa Pham, Richard M. Hoglund, Joel Tarning, Junjie Ding   +4 more
wiley   +1 more source

Levothyroxine treatment and occurrence of fracture of the hip

, 2002
BACKGROUND: Levothyroxine sodium is widely prescribed and has been implicated as a cause of reduction in bone mineral density and, therefore, suggested to be a major contributor to the risk of osteoporotic fractures.
Roger Holder, Sheppard, Michael, Holder, Roger, Franklyn, Jayne, Jayne A. Franklyn, Michael C. Sheppard   +5 more
core   +1 more source

Sex‐ and Region‐Specific Glial Reactivity in Hyperthyroid Mice Lacks Correlation With the Noncognitive and Non‐Depressive‐Like Behavioral Alterations

Brain and Behavior, Volume 16, Issue 6, June 2026.
Hyperthyroidism induces sex‐ and region‐specific glial reactivity without correlation to the noncognitive, non‐depressive behavioral changes in mice. ABSTRACT Background Glial reactivity is implicated in hyperthyroidism‐associated cognitive and psychiatric disorders, yet in vivo imaging evidence of glial reactivity in hyperthyroidism remains to be ...
Qianqian Xue, Zefang Lin, Yaofeng Wang, Xiuting Lin, Yun Yang, Chao Wang, Yuhong Ye, Weibing Miao   +7 more
wiley   +1 more source

Clinical dilemma of mood stabilizer augmentation in treatment‐resistant schizophrenia with residual phase: A case report of valproate‐associated hypoglycemia and cytopenia, and subsequent lithium response

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
Abstract Background Mood stabilizer augmentation is frequently used in treatment‐resistant schizophrenia despite limited guideline recommendations. Evidence for its efficacy and safety in the residual phase, however, remains insufficient. Case Presentation A 49‐year‐old Japanese woman with treatment‐resistant residual schizophrenia exhibited persistent
Yoshiki Kasagi, Naomichi Okamoto, Reiji Yoshimura   +2 more
wiley   +1 more source