Results 11 to 20 of about 30,754 (246)

Prevalence and factors associated with chronic use of levothyroxine: A cohort study. [PDF]

PLoS ONE, 2021
ImportanceLevothyroxine prescriptions are rising worldwide. However, there are few data on factors associated with chronic use.ObjectiveTo assess the prevalence of chronic levothyroxine use, its rank among other chronic drugs and factors associated with ...
Camilla Janett-Pellegri, Lea Wildisen, Martin Feller, Cinzia Del Giovane, Elisavet Moutzouri, Oliver Grolimund, Patrick Walter, Gérard Waeber, Pedro Marques-Vidal, Peter Vollenweider, Nicolas Rodondi   +10 more
doaj   +3 more sources

Levothyroxine monotherapy cannot guarantee euthyroidism in all athyreotic patients. [PDF]

PLoS ONE, 2011
CONTEXT: Levothyroxine monotherapy is the treatment of choice for hypothyroid patients because peripheral T4 to T3 conversion is believed to account for the overall tissue requirement for thyroid hormones.
Damiano Gullo, Adele Latina, Francesco Frasca, Rosario Le Moli, Gabriella Pellegriti, Riccardo Vigneri   +5 more
doaj   +2 more sources

Interchangeability of levothyroxine sodium tablets

Регуляторные исследования и экспертиза лекарственных средств, 2018
The article reviews scientific literature and regulatory documents on safe and efficacious use of levothyroxine medicines. Levothyroxine has less than a twofold difference between the minimal toxic concentration and minimal effective concentration.
G. I. Gorodetskaya, E. A. Sokova, O. V. Muslimova, T. V. Aleksandrova, I. A. Mazerkina, S. G. Rudnev   +5 more
doaj   +1 more source

Investigation of a Stable Interaction of Levothyroxine with AFP Through Molecular Modelling

Cumhuriyet Science Journal
Thyroid dysfunctions are common all over the world, and accordingly, the use of thyroid drugs has increased. Incorrect measurement of tumor markers may lead to missed cases of cancer.
Emel Akbaba, Deniz Karataş, Ataman Gönel, Ezgi Soylu, Beste Kiraz, Yusur Ammar Almahdi   +5 more
doaj   +2 more sources

Massive Pericardial Effusion as a Manifestation of Severe Autoimmune Hypothyroidism in an Adolescent With Down Syndrome: Importance of Early Recognition and Thyroid Hormone Replacement. [PDF]

Clin Case Rep
ABSTRACT The clinical features of severe hypothyroidism may overlap with those of Down syndrome, delaying diagnosis until complications such as myxedema crisis and massive pericardial effusion develop. Regular thyroid function screening is essential, and hypothyroidism‐associated massive pericardial effusion can often be treated conservatively with ...
Mishra B, Pokharel P, Karki A, Rimal O, Bakhrel A, Koirala D, Sapkota R.   +6 more
europepmc   +2 more sources

70 Years of Levothyroxine [PDF]

, 2021
This open access book presents the history, pharmacokinetics and pharmacodynamics of levothyroxine, discussing its role in the thyroid pathophysiology of patients of various ages and during pregnancy.

core   +1 more source

Association of maternal levothyroxine use during pregnancy with offspring birth and neurodevelopmental outcomes: a population-based cohort study

BMC Medicine, 2022
Background The influence of maternal levothyroxine treatment during pregnancy remains unclear. This study aimed to evaluate the associations of maternal levothyroxine treatment during pregnancy with the birth and neurodevelopmental outcomes in offspring.
Grace Mengqin Ge, Edmund C. L. Cheung, Kenneth K. C. Man, Patrick Ip, Wing Cheong Leung, Gloria H. Y. Li, Annie W. C. Kung, Ching-Lung Cheung, Ian C. K. Wong   +8 more
doaj   +1 more source

Effects of levothyroxine substitution therapy on hunger and food intake in individuals with hypothyroidism

Endocrine Connections, 2023
Context: In individuals with hypothyroidism and overweight, levothyroxine substitution therapy is often expected to cause weight loss due to its effect on resting energy expenditure.
Bjarke R Medici, Birte Nygaard, Jeppe L la Cour, Martin Krakauer, Andreas Brønden, Mette P Sonne, Jens J Holst, Jens F Rehfeld, Tina Vilsbøll, Jens Faber, Filip K Knop   +10 more
doaj   +1 more source

Adherence to levothyroxine treatment and factors related with adherence in patients with hypothyroidism

Ankara Medical Journal, 2021
INTRODUCTION: We aimed to evaluate adherence and determine the factors that are related to adherence in patients on levothyroxine therapy. METHODS: Patients older than 18 years old and using levothyroxine for primary hypothyroidism were recruited ...
Ahmet Dirikoç, Birgül Genç, Didem Ozdemir, Abbas Ali Tam, Oya topaloglu, Reyhan Ersoy, Bekir Cakir   +6 more
doaj   +1 more source

Investigating the Effect of Genetic Polymorphisms of Deiodinase Type 2 on Levothyroxine Dose Requirements in Patients with Hypothyroidism

مجله كليه طب الكندي, 2023
Background: Hypothyroidism is the most abundant thyroid disorder worldwide. For decades, levothyroxine was the main effective pharmacological treatment for hypothyroidism. A variety of factors can influence levothyroxine dose, such as genetic variations.
Nada Hamid Rasheed, Basma Zuheir Al-Metwali, Mohamed Sadoon Mohsen Al Shamaa   +2 more
doaj   +1 more source