Results 41 to 50 of about 27,301 (241)

DEVELOPMENT AND IN VITRO CHARACTERIZATION OF POLYMER-BASED NASAL FORMULATIONS OF LEVOTHYROXINE

open access: yes, 2020
BACKGROUND. Hypothyroidism patients, unable to absorb oral levothyroxine rely on expensive and inconvenient intramuscular injections for life-time hormone replacement.
Esomchukwu, Vin-Boris Obinna
core  

Short‐term clinical responses in horses and ponies treated with canagliflozin: A clinical field study

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Treatment with the sodium‐glucose co‐transporter 2 (SGLT2) inhibitor canagliflozin in insulin dysregulated (ID) horses has shown promising results in randomised clinical trials. Larger field studies are needed to further evaluate treatment responses and potential adverse effects under real‐world conditions.
Moa Hällbom   +3 more
wiley   +1 more source

Bioequivalence studies for levothyroxine [PDF]

open access: yesThe AAPS Journal, 2005
The Food and Drug Administration (FDA) Guidance for Bioavailability and Bioequivalence Studies for Levothyroxine has been challenged by companies that manufacture brand-name products. Their contention is that the current guidance does not adequately address the endogenous background levels of the drug, and that the ratios of the PK parameters, a basis ...
openaire   +2 more sources

Fabrication of Levothyroxine Particles Encapsulated with Apatite

open access: yes, 2017
Apatite nuclei were obtained by raising pH of an acellular simulated body fluid (SBF). The apatite nuclei and levothyroxine particles were dispersed in an ultrapure water and the apatite nuclei were attached to the surface of the levothyroxine particles.
Takeshi Yabutsuka   +2 more
core   +1 more source

Propofol‐induced hypertriglyceridemia in critically ill trauma patients requiring nutrition therapy: A descriptive cohort study

open access: yesJournal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background This study aimed to assess the incidence and identify risk factors associated with the development of propofol‐induced hypertriglyceridemia in critically ill trauma patients who required nutrition therapy. Methods Adult patients (aged >17 years) admitted to the trauma intensive care unit who received propofol for >24 h and had a ...
Emma S. Lemke   +5 more
wiley   +1 more source

Choreathetosis due to abuse of levothyroxine

open access: yes, 2009
Choreathetosis due to thyrotoxicosis is a rare movement disorder of acute onset. Here we present the first report of choreathetosis secondary to abuse of levothyroxine.
Kondziella, Daniel,   +2 more
core   +1 more source

Functional constipation in children and young adults with Prader–Willi syndrome

open access: yesJPGN Reports, EarlyView.
Abstract Objectives Prader–Willi Syndrome (PWS) is characterized by hyperphagia, endocrinopathies, and gastrointestinal abnormalities. Clinical concerns about constipation and fecal incontinence (FI) are common, but no studies to date have clear data on functional defecation disorders in children with PWS.
Melinda J. Pierce   +3 more
wiley   +1 more source

Resolution of Levodopa/Dopa‐Decarboxylase Inhibitor—Associated Microscopic Colitis with Subcutaneous Foslevodopa/Foscarbidopa: A Case Series and Review of the Literature

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Microscopic colitis (MC) typically presents with chronic, non‐bloody watery diarrhea. Diagnosis requires endoscopy with colonic mucosal biopsies. The etiology is multifactorial, with several medications implicated, although only a few cases have been attributed to oral levodopa/dopa‐decarboxylase inhibitor (LDDCI) therapy.
Romana Hintner   +10 more
wiley   +1 more source

Dose levotyroxine consumption in hypothyroid patients before dinner change the levels of TSH and T4?

open access: yesCaspian Journal of Internal Medicine, 2015
Background: Levothyroxine is commonly used in the treatment of patients with hypothyroidism. Levothyroxine is often administered in the morning, on an empty stomach, to increase its absorption. However, many patients have trouble for taking levothyroxine
Shahram Ala   +5 more
doaj  

Apalutamide treatment and refractory hypothyroidism: effects of apalutamide on levothyroxine metabolism

open access: yesEuropean Thyroid Journal
Apalutamide, a selective androgen receptor antagonist, is a new treatment for prostate cancer. Among the side effects observed during apalutamide treatment, an increased risk of hypothyroidism has been reported, particularly in patients previously ...
Florie Quattrochi   +2 more
doaj   +1 more source

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