Results 61 to 70 of about 24,240 (205)

Levothyroxine-induced liver injury followed by complete recovery upon cessation of the drug: a case report

Journal of Medical Case Reports, 2019
Background Levothyroxine is a synthetic thyroxine and is the treatment of choice for hypothyroidism. It is a prohormone with minimal intrinsic activity.
Abbas F. Hlaihel, Mudher Z. H. Al-Khairalla   +1 more
doaj   +1 more source

Effect of repeated hot water immersion on cognitive performance, cerebrovascular function, sleep and biomarkers of neurodegeneration in older adults

Experimental Physiology, EarlyView.
Abstract Ageing is associated with cognitive decline and increased risk of developing neurodegenerative disease. Repeated passive heating, using hot water immersion (HWI), may improve cognitive performance via improved cerebral oxygenation, but this is yet to be examined in older adults.
Daniel D. Piccolo, Jo Corbett, Joseph T. Costello, Thomas B. Williams, Thomas J. James, Janis K. Shute, Mohammad G. A. Alnajjar, Luke C. Hudson, Poppy A. Marsh, Veronika Praskacova, Harry S. Mayes, Michael Tipton, Maria Perissiou, Melitta A. McNarry, Kelly A. Mackintosh, Zoe L. Saynor, Anthony I. Shepherd   +16 more
wiley   +1 more source

Effect of repeated hot water immersion on muscle strength, power, function and physical activity in healthy older adults: A randomised crossover trial

Experimental Physiology, EarlyView.
Abstract Ageing leads to an increased prevalence of sarcopenia and frailty, characterised by progressive declines in muscle strength, power and function and reduced physical activity. Hot water immersion (HWI) could potentially improve muscle function, but this is yet to be explored in older adults.
Daniel D. Piccolo, Jo Corbett, Timothy A. Exell, Joseph M. Moore, Amy Wright, Mohammad G. A. Alnajjar, Luke C. Hudson, Poppy A. Marsh, Veronika Praskacova, Melitta A. McNarry, Kelly A. Mackintosh, Zoe L. Saynor, Anthony I. Shepherd   +12 more
wiley   +1 more source

Combination Thyroid Hormone Replacement; Knowns and Unknowns

Frontiers in Endocrinology, 2019
Hypothyroidism is common throughout the world and readily diagnosed with thyroid function tests. Management should be straightforward but appears not to be the case.
Peter N. Taylor, Vinay Eligar, Ilaria Muller, Anna Scholz, Colin Dayan, Onyebuchi Okosieme   +5 more
doaj   +1 more source

The acute effects of exercise intensity and inorganic nitrate supplementation on the Buckberg ratio in postmenopausal females

Experimental Physiology, EarlyView.
Abstract Menopause increases coronary heart disease risk, in part through reduced oestrogen‐mediated nitric oxide (NO) bioavailability. The Buckberg ratio, an index of myocardial oxygen supply–demand balance, in which higher values reflect more favourable myocardial perfusion, is lower in postmenopausal females (PMFs) than in age‐matched males.
Cassandra C. Derella, Austin C. Hogwood, Joaquin Ortiz de Zevallos, Nathan R. Weeldreyer, Kaitlin M. Love, Arthur Weltman, Jason D. Allen   +6 more
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

The relationship between levothyroxine dosage and free thyroxine levels in hypothyroid patients: a large retrospective study

European Thyroid Journal
Objective: This study examined the relationship between levothyroxine dosage and free thyroxine levels in hypothyroid patients. The aim was to ascertain whether elevated free thyroxine in treated patients suggests overmedication or is essential for ...
Toshihiko Kasahara
doaj   +1 more source

Hypothyroidism resulting from follicular‐compact thyroid carcinoma in a dog

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 13‐year‐old, spayed, female beagle, weighing 21 kg, was presented with a cervical nodule that had appeared about 15 days earlier. On palpation, a firm, slightly mobile mass measuring approximately 4 cm in diameter was detected in the thyroid region.
Júlio César Nascimento de Cerqueira Júnior, Teresa Alessandra de Lima Núñez, Ana Beatriz de Souza da Silva, Alessandre Hataka, Priscylla Tatiana Chalfun Guimarães Okamato   +4 more
wiley   +1 more source

The Homozygous p.(Arg215Ter) Variant in XRCC2 Is Associated With Atypical Fanconi Anemia Without Major Hematological Abnormalities in Childhood

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2331-2337, October 2026.
ABSTRACT Fanconi Anemia (FA) is the most frequent inherited bone marrow failure syndrome. A role for the XRCC2 gene in FA was suspected in 2012 and confirmed in 2016, but only two affected individuals have been described thus far, and no long‐term follow‐up is available.
Sabina Cenciarelli, Giulia Bruna Marchetti, Maria Iascone, Maria Grazia Patricelli, Sara Giangiobbe, Gabriella Cinzia Pozzobon, Miriam Nella Savini, Fabio Giglio, Alessandro Aiuti, Paola Carrera, Francesca Ferrua, Angela Peron   +11 more
wiley   +1 more source

Semaglutide therapy and iatrogenic thyrotoxicosis

Endocrinology, Diabetes & Metabolism Case Reports
Levothyroxine is the backbone of hypothyroidism treatment. The dosage of levothyroxine varies; however, as an estimate, an average adult patient will require 1.6 micrograms per kilogram of body weight. We present the case of a patient with hypothyroidism,
Maxim John Levy Barnett, Sarah Eidbo, Ana Rivadeneira   +2 more
doaj   +1 more source