Results 61 to 70 of about 37,295 (269)

Pituitary hyperplasia mimicking macroadenoma associated with primary hypothyroidism in a patient with selective L-thyroxine malabsorption [PDF]

open access: yes, 2017
We present the case of a 29-year-old woman who developed a severe hypothyroidism induced by a thyroxine malabsorption and a secondary pituitary hyperplasia.
Romanelli, Francesco   +4 more
core   +1 more source

The Clinical Significance of Subclinical Thyroid Dysfunction. [PDF]

open access: yes, 2008
Subclinical thyroid disease (SCTD) is defined as serum free T(4) and free T(3) levels within their respective reference ranges in the presence of abnormal serum TSH levels.
BIONDI, BERNADETTE, COOPER DS
core   +1 more source

A hidden cause of infertility in hypothyroid patients [PDF]

open access: yes, 2020
Methylene tetrahydrofolate reductase (MTHFR) gene mutations could be the cause of infertility in hypothyroid patients. Hence, it is worthy to screen for MTHFR gene mutations in infertile hypothyroid females and their partners if infertility persists ...
Ahmed, Soha Magdy   +4 more
core   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

The Role of Immune Checkpoint Inhibitors in Adrenocortical Carcinoma: Enhancing Post‐Surgical Outcomes and Overcoming Relapse

open access: yesMedicine Advances, EarlyView.
Adrenocortical carcinoma (ACC) is a rare and aggressive cancer that's usually detected at an advanced stage and has a high recurrence rate despite surgical resection, making treatment challenging. Although mitotane is still the only approved treatment, its poor effectiveness has raised interest in immunotherapy with immune checkpoint inhibitors (ICIs ...
Jawairya Muhammad Hussain   +5 more
wiley   +1 more source

Effect of Levothyroxine on Older Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Endocrinology, 2022
BackgroundSubclinical hypothyroidism (SCH) is usually treated with levothyroxine, but there is controversy as to whether SCH should be treated, especially for older patients.
Chunyan Zhao   +3 more
doaj   +1 more source

Qualitative study on occupational anxiety among young thyroid cancer survivors before returning to work

open access: yesPrecision Medical Sciences, EarlyView.
The main aim of this study was to elucidate and clarify the manifestations of occupational anxiety among young postoperative thyroid cancer survivors before returning to work and to explore strategies and support needed to cope upon their return to work. Abstract The purpose of this qualitative study was to understand the manifestations of occupational
Hong Gao   +10 more
wiley   +1 more source

Liquid Levothyroxine: Efficacy and Application in the Treatment of Myxoedema Coma - A Narrative Review

open access: yesQuality in Sport
Introduction: Myxoedema coma is a severe and rare manifestation of hypothyroidism that requires immediate and effective intervention. Traditional treatment involves the use of levothyroxine, a synthetic thyroid hormone.
Patrycja Nowoświat   +10 more
doaj   +1 more source

Thyroid-hormone therapy and thyroid cancer: a reassessment. [PDF]

open access: yes, 2005
Experimental studies and clinical data have demonstrated that thyroid-cell proliferation is dependent on thyroid-stimulating hormone (TSH), thereby providing the rationale for TSH suppression as a treatment for differentiated thyroid cancer.
BIONDI, BERNADETTE   +2 more
core  

Food interactions with levothyroxine

open access: yes, 2021
Levothyroxine, a synthetic thyroid hormone, was the most prescribed drug in the USA in the past three years. Levothyroxine is applied as substitution therapy in hypothyroidism (both primary and central) and also recommended after a thyroidectomy (without hypothyroidism) for the prevention of recurrences, for the inhibition of nodular goitre growth ...
Milošević, Nataša   +3 more
openaire   +2 more sources

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