Results 61 to 70 of about 36,523 (215)

Hypothyroidism and the increased risk of preeclampsia – interpretative factors?

Hypertension in Pregnancy, 2020
Objective To evaluate the causes behind the association between hypothyroidism and the risk of preeclampsia. Methods Checking of individual hospital and birth records from 149 levothyroxine users among 2,508 women in the preeclampsia case–control study ...
Aino Lintula, Leea Keski-Nisula, Heidi Sahlman   +2 more
doaj   +1 more source

Deep phenotyping of heart failure with preserved ejection fraction through multi‐omics integration

European Journal of Heart Failure, EarlyView.
Deep phenotyping of of heart failure with preserved ejection fraction (HFpEF) through multi‐omics integration. AI, artificial intelligence. Aims Heart failure with preserved ejection fraction (HFpEF) has become the predominant form of heart failure and a leading cause of global cardiovascular morbidity and mortality.
Jakob Versnjak, Titus Kuehne, Pauline Fahjen, Nina Jovanovic, Ulrike Löber, Gabriele G. Schiattarella, Nicola Wilck, Holger Gerhardt, Dominik N. Müller, Frank Edelmann, Philipp Mertins, Roland Eils, Michael Gotthardt, Sofia K. Forslund, Benjamin Wild, Marcus Kelm   +15 more
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism.

Journal of the American Medical Association (JAMA), 2019
Importance It is unclear whether levothyroxine treatment provides clinically important benefits in adults aged 80 years and older with subclinical hypothyroidism.
S. Mooijaart, R. Puy, D. Stott, P. Kearney, N. Rodondi, R. Westendorp, W. Elzen, I. Postmus, R. Poortvliet, D. Heemst, Barbara C. van Munster, R. Peeters, I. Ford, S. Kean, C. Messow, M. Blum, M. Blum, T. Collet, T. Watt, O. Dekkers, J. Jukema, J. A. Smit, P. Langhorne, J. Gussekloo   +23 more
semanticscholar   +1 more source

IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak, Daniella Magen, Karin Weiss, Tamar Paperna, Suhair Hanna, Amos Etzioni, Adi Miller‐Barmak, Yonatan Butbul Aviel   +7 more
wiley   +1 more source

Levothyroxine monotherapy cannot guarantee euthyroidism in all athyreotic patients. [PDF]

PLoS ONE, 2011
CONTEXT: Levothyroxine monotherapy is the treatment of choice for hypothyroid patients because peripheral T4 to T3 conversion is believed to account for the overall tissue requirement for thyroid hormones.
Damiano Gullo, Adele Latina, Francesco Frasca, Rosario Le Moli, Gabriella Pellegriti, Riccardo Vigneri   +5 more
doaj   +1 more source

Qualitative study on occupational anxiety among young thyroid cancer survivors before returning to work

Precision Medical Sciences, EarlyView.
The main aim of this study was to elucidate and clarify the manifestations of occupational anxiety among young postoperative thyroid cancer survivors before returning to work and to explore strategies and support needed to cope upon their return to work. Abstract The purpose of this qualitative study was to understand the manifestations of occupational
Hong Gao, Ping Zhu, Maomao Zhang, Bing Wu, Yun Ning, Xiaoxu Li, Hui Huang, Jinlan Shao, Meiying Zou, Tingting Hu, Liuliu Zhang   +10 more
wiley   +1 more source

Plain Language Summary of the ACCEPT Guideline for the Management of Recurrent Pregnancy Loss

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Recurrent pregnancy loss (RPL) is when a woman experiences two or more pregnancy losses. Investigating for causes of RPL can provide an explanation and possible treatment options. This is a summary of Parts 1 and 2 of Australasian Recurrent Pregnancy Loss Clinical Management Guidelines in an easy‐to‐read patient friendly format. These original
Adriana Suker, Ying Li, Anthony Marren, Danielle Robson, the Australasian CREI (Certificate of Reproductive Endocrinology and Infertility) Consensus Expert Panel on Trial evidence (ACCEPT) group   +4 more
wiley   +1 more source

Change in levothyroxine requirements after bariatric surgery in patients with hypothyroidism

Endocrine Regulations, 2021
Objectives. This study aims to evaluate the need to modify the total and weight-adjusted doses of levothyroxine after bariatric surgery, identify predictors, and assess the influence of the weight loss on the levothyroxine requirements. Methods.
R. García-Moreno, A. C. Blanco, I. Vinuela, M. Larrauri, L. Morena   +4 more
semanticscholar   +1 more source

ACCEPT Group Condensed Position Paper on the Management of Recurrent Pregnancy Loss

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT The Australasian CREI (Certificate of Reproductive Endocrinology and Infertility) Consensus Expert Panel on Trial Evidence (ACCEPT) group recently published an evidence‐based guideline on the investigation and management of recurrent pregnancy loss (RPL).
Adriana Suker, Ying Li, Anthony Marren, Danielle Robson, the Australasian CREI (Certificate of Reproductive Endocrinology and Infertility) Consensus Expert Panel on Trial evidence (ACCEPT) Group   +4 more
wiley   +1 more source