Results 141 to 150 of about 11,952,476 (292)

Identification of Compound Heterozygous CYP11A1 Variants via Reanalysis of Clinical Sequencing Data

American Journal of Medical Genetics Part A, Volume 200, Issue 4, Page 923-928, April 2026.
ABSTRACT A molecular diagnosis is currently achievable in approximately 50% of patients assessed by clinical geneticists at tertiary care centres. Next‐Generation Sequencing Panels contain a defined group of genes associated with a clinically defined set of phenotypes.
Ana Acosta Bedón, Vahid Akbari, Ralph Rothstein, Alexandra Inman, Sanjiv Bhalla, Jianghong An, Jan M. Friedman, Rosanna Weksberg, Cornelius Boerkoel, Steven J. M. Jones, William T. Gibson   +10 more
wiley   +1 more source

Prepubertal Diabetes Stagnates Testicular Development by Skewing Autophagy Homeostasis in Leydig Cells

Cells
The maturation of testicular Leydig cells during the prepubertal stage is crucial for establishing male fertility. While diabetes is recognized as a significant detrimental factor affecting male testicular function, its impact specifically during the ...
Zonghao Tang, Youkun Zheng
doaj   +1 more source

Leydig cell

Citation: 'Leydig cell' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10891 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

The Diagnostic Promise of Serum S100B Protein in Pregnancy‐Related Hypertension: A Narrative Review

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background Hypertensive disorders of pregnancy (HDP) are a major cause of illness and death for mothers and babies worldwide. Their number is rising due to older maternal age, obesity, and other health problems. Early diagnosis is important. Serum protein S100B, a calcium‐binding protein studied in brain diseases, is now being considered as a ...
Moldir Dossimbetova, Nurgul Ablakimova, Lazzat Balymbetova, Andrei Gaiday, Kazbek Yermagambetov, Saule Bermagambetova, Mukhit Sarsembayev, Gulnara Gubasheva, Andrii Dinets, Akylbek Tussupkaliyev   +9 more
wiley   +1 more source

A Boy with 46,XX Karyotype (SRY Double-positive) and a Leydig Cell Tumor

JCRPE
Leydig cell tumors are the most common type of testicular sex cord stromal tumors. The presence of the Y chromosome is associated with tumor risk in sex development disorders (DSD), however tumor development without Y chromosome is extremely rare.
Merve Güllü, Sultan Aydın, Tarkan Kalkan, Tangül Pınarcı, Doğa Türkkahraman   +4 more
doaj   +1 more source

Hypoxia drives spermatogenic impairment by triggering lysosome-dependent death of Leydig cells via M1 macrophage polarization

陆军军医大学学报
Objective To investigate the critical role of hypoxia in impairing spermatogenesis via M1 macrophage polarization and subsequent induction of lysosome-dependent cell death (LDCD) in Leydig cells. Methods Ten eight-week-old male SD rats (weight 220~250
MENG Dan, HE Wei, ZENG Jitao
doaj   +1 more source

C-Type Natriuretic Peptide/Natriuretic Peptide Receptor 2 Is Involved in Cell Proliferation and Testosterone Production in Mouse Leydig Cells

The World Journal of Men's Health, 2019
Purpose: This study investigated the role of natriuretic peptide receptor 2 (NPR2) on cell proliferation and testosterone secre-tion in mouse Leydig cells.Materials and Methods: Mouse testis of different postnatal stages was isolated to detect the ...
Lei Yang, Lanjie Lei, Qihan Zhao, Ying Gong, Gaopeng Guan, Shaoxin Huang   +5 more
doaj   +1 more source

Ethylene dimethanesulfonate effects on gene promoter activities related to the endocrine function of immortalized Leydig cell lines R2C and MA-10

Current Research in Toxicology
Ethylene dimethanesulfonate (EDS) is a molecule with known selective cytotoxicity on adult Leydig cells. A single intraperitoneal injection in rats but not mice, leads to male androgen deprivation and infertility.
Jorge W.F. de Barros, Kenley Joule Pierre, Wilma De G. Kempinas, Jacques J. Tremblay   +3 more
doaj   +1 more source

A contribution to the knowledge of the skin albuminose cells of Torpedo ocellata Raf [Riv.Istochim.norm.pat. 8 411-416, 1962] [PDF]

, 1979
Glandular cells, other than the mucous cells, have been described in the skin of various groups of fish (Teleosts, Ganoids, Selachii) and they have been called 'albuminose' by various authors. The authors propose to study the albuminose cells in the skin
Celada, M., De Paoli, A. M.
core  

Formaldehyde exposure induces histopathological and morphometric changes in the rat testis [PDF]

, 2007
Formaldehyde is a chemical which is traditionally used for fixing cadavers and routine histopathology techniques. It is vaponsed during the dissection and practical study of a cadaver.
Azarhoush, R., Davarian, A., Fazeli, S.A., Ghafari, S., Gharravi, A.M., Golalipour, M.J.   +5 more
core