Results 81 to 90 of about 11,952,476 (292)
Cell Research, 2014 The ability to identify and isolate lineage-specific stem cells from adult tissues could facilitate cell replacement therapy. Leydig cells (LCs) are the primary source of androgen in the mammalian testis, and the prospective identification of stem Leydig
M. Jiang +15 more
semanticscholar +1 more source
iMetaOmics, EarlyView.SPARK is an interactive platform hosting 189,232 human testicular single‐cell transcriptomes across normal and infertile conditions. It enables automated, code‐free analysis and visualization, providing a powerful resource to explore cellular and molecular dynamics in male reproduction and infertility.
Lina Cui +9 more
wiley +1 more source
A Sertoli-Leydig ovarian tumor presenting as ovarian torsion: A case report
Case Reports in Women's HealthTorsion occurs as a complication in 10% of cases of ovarian tumors. It predominantly occurs in benign ones, while malignant tumors are less prone to torsion.
Samia Tligui +6 more
doaj +1 more source
Abnormal proliferation of Leydig cells in Sox30 knockout mice
Di-san junyi daxue xuebao, 2021 Objective To investigate the effect of Sox30 gene knockout on the proliferation of mouse Leydig cells. Methods The pathological morphology of the testis of 10-week-old Sox30+/+, Sox30-/+ and Sox30-/- mice was observed with HE staining ...
TANG Ying +5 more
doaj +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Gold has been used for centuries in both ornamental and medicinal contexts. More recently, gold compounds, containing ions or nanoparticles, have attracted attention for their anti‐inflammatory, anticancer, and diagnostic applications. Therefore, concerns about systemic toxicity and biodistribution have prompted investigations into the ...
Samira Maghraoui +2 more
wiley +1 more source
THE EFFECTS OF VITAMIN C ON GLYCIDAMIDE-INDUCED CELLULAR DAMAGE AND APOPTOSIS IN MOUSE LEYDIG CELLS
Trakya University Journal of Natural Sciences, 2019 The aim of this study was to elucidate the role of vitamin C on glycidamide-induced cytotoxicity, oxidative damage and cell death in Leydig (TM3) cells.
Banu Orta Yılmaz
doaj +1 more source
Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.ABSTRACT Animals with seasonal reproductive cycles, as the Roe deer (Capreolus capreolus), have developed mechanisms to synchronize reproduction with the environmental cycle in order to optimize reproductive success through melatonin. Angiogenesis and oxidative stress are key processes in spermatogenesis, contributing to testicular remodeling and ...
Ilaria Troisio +7 more
wiley +1 more source
Malignant Leydig Cell Tumor in Elderly Complete Androgen Insensitivity Patient: A Case Report
Journal of Nepal Medical Association, 2019 There are various cause of Primary amenorrhea in phenotypically females such as, complete androgen insensitivity syndrome, pure gonadal dysgenesis, 17b-hydroxysteroid dehydrogenase deficiency, or mixed gonadal dysgenesis.
Sundar Shrestha +3 more
doaj +1 more source
Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)
Phytotherapy Research, EarlyView.ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley +1 more source
Virilization in a postmenopausal female due to androgen secreting ovarian dermoid cyst
Journal of Mid-Life Health, 2017 Virilizing ovarian dermoid cysts are very rare. The source of androgen in these cysts may be tumors such as Sertoli–Leydig cell tumor or Leydig cell hyperplasia.
Murali Subbaiah +3 more
doaj +1 more source