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Urology, 1979
In adult patients with Leydig cell tumor of the testis, endocrinologic signs occur in 30 per cent of the cases and often precede the onset of a palpable testicular mass. Gynecomastia is the most common endocrinologic manifestation and probably is due to increased estrogen secretion by the Leydig cells.
A A, Caldamone +3 more
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In adult patients with Leydig cell tumor of the testis, endocrinologic signs occur in 30 per cent of the cases and often precede the onset of a palpable testicular mass. Gynecomastia is the most common endocrinologic manifestation and probably is due to increased estrogen secretion by the Leydig cells.
A A, Caldamone +3 more
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Archives of Gynecology and Obstetrics, 2001
Sertoli-Leydig cell tumors belong to the group of sex-cord stromal tumors of the ovary. They account for less than 0,5% of all ovarian neoplasms. The majority of these tumors are benign, and almost all are localised unilaterally. Herewith, we describe an ovarian Sertoli-Leydig cell tumor in an 11-year-old girl.
T, Lantzsch +5 more
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Sertoli-Leydig cell tumors belong to the group of sex-cord stromal tumors of the ovary. They account for less than 0,5% of all ovarian neoplasms. The majority of these tumors are benign, and almost all are localised unilaterally. Herewith, we describe an ovarian Sertoli-Leydig cell tumor in an 11-year-old girl.
T, Lantzsch +5 more
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INSL3 Expression in Leydig Cell Hyperplasia and Leydig Cell Tumors
Applied Immunohistochemistry & Molecular Morphology, 2019Insulin-like 3 (INSL3) is a hormone produced by Leydig cells (LCs) and leads to physiological testicular descent during embryonic development. We investigated the expression of INSL3 by immunohistochemistry in normal LCs, in Leydig cell tumor (LCT) (n=17 including 15 testes and 2 ovaries) and in Leydig cell hyperplasia (LCH) (n=10).
Nelli S, Lakis +5 more
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Metastasized Leydig cell tumor in a dog
Schweiz Arch Tierheilkd, 2015We present the clinical findings, diagnosis and treatment of an 11-year old intact male Fox Terrier with a malignant Leydig cell tumor of the right testicle, which metastasized to the skeletal musculature of the left hind limb. The primary tumor and the metastasis were resected with narrow margins. The dog was treated with metronomic chemotherapy using
A, Togni +3 more
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Leydig cell tumor in identical twin
Urology, 1976A case is presented of an identical twin who had an interstitial cell tumor of the testis removed, and comparison is made with his identical brother over an ensuing six-year period. The dramatic effects of the interstitial cell tumor are clearly shown in the comparison of the two males over this six-year period.
W R, Turner, F C, Derrick, H, Wohltmann
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[Leydig-cell tumors of the testicle].
Annali italiani di chirurgia, 1990Leydig's cells tumor account for 1-2% of all testicular tumors. The authors report a rare case of benign Leydig's cells tumor in a young man with gynecomastia. They examine the embryogenesis, the hormonal modifications, the criteria of malignancy, the treatment and results. They present a review of the literature pertaining to this rare tumors.
GUERRIERO O +5 more
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A malignant Leydig cell tumor of the testis
International Urology and Nephrology, 2006A 40-year-old man was referred to our hospital with gynecomastia and painless swelling of the right scrotum. Ultrasonography revealed a 15 x 10 mm mass with low echogenicity of the right testis. We performed right high orchiectomy. Histologically, Reinke's crystals and capsular invasion by tumor cells were found.
Koichi, Sugimoto +6 more
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LEYDIG CELL TUMORS PRESENTING AS AZOOSPERMIA
Journal of Urology, 1999Leydig cell tumors of the testis are rare, comprising 1 to 3% of all testicular neoplasms.l.2 Approximately 10% of these tumors are malignant. They most commonly present as a testicular mass or with endocrine abnormalities, such as gynecomastia and loss of libido.
M L, Fallick, W W, Lin, L I, Lipshultz
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The Diagnosis of Leydig Cell Tumors in Childhood
Archives of Pediatrics & Adolescent Medicine, 1978We report the clinical and hormonal findings in two boys with isosexual precocity secondary to Levdig cell tumor of the testis. The hormonal profile at the initial evaluation was quite different in the two cases suggesting differences in steroid biosynthesis by the tumors. These differences indicate that a dexamethasone suppression test may be required
M D, Urban +3 more
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Leydig cell tumor and hyperplasia: a review.
Analytical and quantitative cytology and histology, 2007We describe the role of Leydig cells in normal, hyperplastic and neoplastic testis. Recent acquisitions on etiology and pathobiology of Leydig cell proliferations, unusual microscopic presentations and clinical and morphologic features predictive of malignancy are reported.
M. Colecchia +6 more
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