Results 161 to 170 of about 23,359 (215)
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Congenital Leydig cell hyperplasia
Histopathology, 1988The testes and epididymes collected at autopsy from 21 newborns showed apparent Leydig cell hyperplasia which was studied by light and electron microscopy. Twelve newborns were the sons of diabetic mothers, two had undergone rhesus isoimmunization, two were twins of a non‐diabetic mother, three had Beckwitz‐Widemann's syndrome, and two had ...
M, Nistal +2 more
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Archives of Andrology, 1986
The ultrastructure of Leydig cell hyperplasia is described. The hyperplastic Leydig cells differ morphologically from normal Leydig cells as well as from Leydig tumor cells. They have less smooth endoplasmic reticulum and less lipofuscin pigment in their cytoplasm, and the nuclear membrane shows more irregular indentations than normal Leydig cells.
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The ultrastructure of Leydig cell hyperplasia is described. The hyperplastic Leydig cells differ morphologically from normal Leydig cells as well as from Leydig tumor cells. They have less smooth endoplasmic reticulum and less lipofuscin pigment in their cytoplasm, and the nuclear membrane shows more irregular indentations than normal Leydig cells.
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Archives of Gynecology and Obstetrics, 2001
Sertoli-Leydig cell tumors belong to the group of sex-cord stromal tumors of the ovary. They account for less than 0,5% of all ovarian neoplasms. The majority of these tumors are benign, and almost all are localised unilaterally. Herewith, we describe an ovarian Sertoli-Leydig cell tumor in an 11-year-old girl.
T, Lantzsch +5 more
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Sertoli-Leydig cell tumors belong to the group of sex-cord stromal tumors of the ovary. They account for less than 0,5% of all ovarian neoplasms. The majority of these tumors are benign, and almost all are localised unilaterally. Herewith, we describe an ovarian Sertoli-Leydig cell tumor in an 11-year-old girl.
T, Lantzsch +5 more
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INSL3 Expression in Leydig Cell Hyperplasia and Leydig Cell Tumors
Applied Immunohistochemistry & Molecular Morphology, 2019Insulin-like 3 (INSL3) is a hormone produced by Leydig cells (LCs) and leads to physiological testicular descent during embryonic development. We investigated the expression of INSL3 by immunohistochemistry in normal LCs, in Leydig cell tumor (LCT) (n=17 including 15 testes and 2 ovaries) and in Leydig cell hyperplasia (LCH) (n=10).
Nelli S, Lakis +5 more
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Malignant Feminizing Leydig Cell Tumor
Journal of Urology, 1984AbstractA patient with a feminizing malignant Leydig cell tumor is presented. Hormonal assays revealed increased production of prolactin, estradial, and total estrogens. Eleven years after the onset of his disease he remains clinically well.
C M, Shapiro, A, Sankovitch, W J, Yoon
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2007
The discovery of adult Leydig cells by Franz Leydig in 1850 led to extensive research into the functions and regulation of this testis-specific cell type (1). In the early 1900s, Whitehead presented the first extensive analysis of fetal Leydig cells (FLCs) in pig embryos, staging the idea that a distinct Leydig cell population exists in fetal testes (2,
Humphrey Hung-Chang Yao, Ivraym Barsoum
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The discovery of adult Leydig cells by Franz Leydig in 1850 led to extensive research into the functions and regulation of this testis-specific cell type (1). In the early 1900s, Whitehead presented the first extensive analysis of fetal Leydig cells (FLCs) in pig embryos, staging the idea that a distinct Leydig cell population exists in fetal testes (2,
Humphrey Hung-Chang Yao, Ivraym Barsoum
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Leydig Cell in Idiopathic Varicocele
European Urology, 1990In a group of 31 patients with idiopathic varicocele (IV), testicular biopsy showed a decreased tubular diameter, hyperplasia in the number of Leydig's cells (LC; many with cytoplasmic vacuolization and atrophy) and a decrease in the number of positive LC in testicular tissue sections stained with the testosterone peroxidase-antiperoxidase method ...
J J, Sirvent +5 more
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2008
This boy, age 3 years and 9 months, was referred for precocious puberty. He had pubarche 6 months prior to presentation. His genitalia had always seemed to be larger than his older brother’s genitalia; they had increased in size over the 4 to 6 months prior to presentation. He also had recent acceleration of growth in height.
Courtney Finlayson +2 more
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This boy, age 3 years and 9 months, was referred for precocious puberty. He had pubarche 6 months prior to presentation. His genitalia had always seemed to be larger than his older brother’s genitalia; they had increased in size over the 4 to 6 months prior to presentation. He also had recent acceleration of growth in height.
Courtney Finlayson +2 more
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Archivos espanoles de urologia, 1989
We report on a 54-year-old male patient with Leydig cell tumor of testis, an incidental finding following orchiectomy for a testicular tumor. The pathological findings met the established histologic criteria for a benign tumor. The patient required no other treatment. The results of hormonal analyses were hormonal.
J A, Zabala Egurrola +5 more
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We report on a 54-year-old male patient with Leydig cell tumor of testis, an incidental finding following orchiectomy for a testicular tumor. The pathological findings met the established histologic criteria for a benign tumor. The patient required no other treatment. The results of hormonal analyses were hormonal.
J A, Zabala Egurrola +5 more
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