Results 91 to 100 of about 12,270 (235)
A Retrospective Study on the Impact of Primary Aldosteronism in Pregnancy (H.A.P.P.I. Study Group)
Clinical Endocrinology, Volume 104, Issue 2, Page 113-122, February 2026.ABSTRACT Objective Primary aldosteronism (PA) is a common cause of hypertension in young women. However, there is a paucity of data regarding its impact during pregnancy. The primary objective of this study was to describe the occurrence of hypertensive disorders of pregnancy (HDP) in PA.
Diana Oprea +7 more
wiley +1 more source
Lhcgr Expression in Granulosa Cells: Roles for PKA-Phosphorylated β-Catenin, TCF3, and FOXO1
Molecular Endocrinology, 2013 Ovarian follicles lacking FSH or FSH receptors fail to progress to a preovulatory stage, resulting in infertility. One hallmark of the preovulatory follicle is the presence of luteinizing hormone/choriogonadotropin receptors (LHCGR) on granulosa cells (GCs). However, the mechanisms by which FSH induces Lhcgr gene expression are poorly understood.
Law, Nathan C +4 more
openaire +4 more sources
A functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production [PDF]
, 2013 Bone morphogenetic proteins (BMP) are firmly implicated as intra-ovarian regulators of follicle development and steroidogenesis. Here we report a microarray analysis showing that treatment of cultured bovine theca cells (TC) with BMP6 significantly (>2 ...
Anand-Ivell +47 more
core +1 more source
CellsJuvenile angiofibroma (JA) is a rare, sex-specific, and highly vascularized nasal tumor that almost exclusively affects male adolescents, but its etiology has been controversial.
Silke Wemmert +6 more
doaj +1 more source
The Journal of Reproduction and Development, 2021 During oocyte growth and follicle development, oocytes closely communicate with cumulus cells. We examined the effects of oocyte-derived growth factors, growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15), on the growth and ...
Riho MORIKAWA, Jibak LEE, Takashi MIYANO
doaj +1 more source
Importância do estudo multigénico no diagnóstico molecular de doenças raras por sequenciação de nova geração [PDF]
, 2019 Introdução: A sequenciação de nova geração (NGS) revolucionou o diagnóstico molecular das doenças raras (DR) proporcionando a análise de um maior número de genes, resultados mais rápidos e custos reduzidos. A NGS usando diferentes abordagens, possibilita
Gonçalves, João +4 more
core
Histopathology, Volume 88, Issue 1, Page 230-251, January 2026.In this review, we summarise the major recent advances in Testicular Sex Cord‐Stromal Tumours, focusing on molecular alterations and biomarkers relevant for diagnosis, classification and prognosis. Testicular sex cord‐stromal tumours (TSCSTs) represent ~4%–8% of all testicular neoplasms.
João Lobo, Andres M Acosta
wiley +1 more source
CGB activates ERK and AKT kinases in cancer cells via LHCGR-independent mechanism
Tumor Biology, 2014 Expression of human chorionic gonadotropin free beta subunit (hCGβ) and its hyperglycosylated variant (hCGβ-H) is a phenomenon confirmed for tumors of different origin. Despite numerous studies, the mechanism of hCGβ action in cancer remains unknown especially that not all tumors secreting hCGβ express the receptor for human chorionic gonadotropin ...
Aleksandra, Głodek, Anna, Jankowska
openaire +2 more sources
Hormonal and Allosteric Regulation of the Luteinizing Hormone/Chorionic Gonadotropin Receptor
Frontiers in Bioscience-LandmarkLuteinizing hormone (LH) and human chorionic gonadotropin (CG), like follicle-stimulating hormone, are the most important regulators of the reproductive system.
Alexander O. Shpakov
doaj +1 more source
Scientific Reports, 2022 The genetic background of feline disorders of sex development (DSDs) is poorly understood. We performed comprehensive cytogenetic, molecular, and histological studies of 17 cats with abnormal external genitalia, unusual behavior, or tricolor coats ...
Monika Stachowiak +12 more
doaj +1 more source