Results 91 to 100 of about 11,587 (188)

Enhancing endometrial receptivity: the roles of human chorionic gonadotropin in autophagy and apoptosis regulation in endometrial stromal cells

Reproductive Biology and Endocrinology
Inadequate endometrial receptivity often results in embryo implantation failure and miscarriage. Human chorionic gonadotropin (hCG) is a key signaling molecule secreted during early embryonic development, which regulates embryonic maternal interface ...
Bin Wang, Mingxia Gao, Ying Yao, Haofei Shen, Hongwei Li, Jingjing Sun, Liyan Wang, Xuehong Zhang   +7 more
doaj   +1 more source

Clinical, biological and genetic analysis of prepubertal isolated ovarian cyst in 11 girls.

PLoS ONE, 2010
BackgroundThe cause of isolated gonadotropin-independent precocious puberty (PP) with an ovarian cyst is unknown in the majority of cases. Here, we describe 11 new cases of peripheral PP and, based on phenotypes observed in mouse models, we tested the ...
Raja Brauner, Anu Bashamboo, Sébastien Rouget, Marie Goulet, Pascal Philibert, Hélène Sarda-Thibault, Christine Trivin, Micheline Misrahi, Charles Sultan, Ken McElreavey   +9 more
doaj   +1 more source

Permissive but not causative: layer-specific LHCGR alterations in ovarian aging

npj Aging
Abstract The ovary is among the earliest organs to show clinically consequential age-related decline. The luteinizing hormone/choriogonadotropin receptor (LHCGR) mediates the trophic actions of LH and human chorionic gonadotropin (hCG) in the ovary, and reduced receptor abundance has sometimes been invoked as a possible explanation ...
Hongbo Wu, Zhao Zhang, Liyan Huang, Shuling Wang, Zhenghong Chen, Min Lu, Weiling Tang, Jingwen Chen, Yiling Xie, Lidan Liu   +9 more
openaire   +1 more source

Screening of follicle-stimulating hormone dose-dependent expression genes

浙江大学学报. 农业与生命科学版, 2018
To develop a new and effective method for detection of follicle-stimulating hormone (FSH) bioactivity, porcine follicular granulosa cells were used as experimental materials, and expression of genes in FSH-treated group (40 mIU/mL) and blank control ...
LIU Tian, CHEN Xiaoyu, ZHU Zhiwei, YU Fuxian, HUANG Jing, JIA Ruoxin, SHI Fangxiong, PAN Jianzhi   +7 more
doaj   +1 more source

Novel compound heterozygous variants in the LHCGR gene identified in a subject with Leydig cell hypoplasia type 1

, 2018
Background: Leydig cell hypoplasia (LCH) is a rare disease and one of the causes of male disorder of sexual differentiation (DSD). Inactivating mutations in the luteinizing hormone/chorionic gonadotropin receptor (LHCGR) gene account ...
Yufei Xu, Niu Li, Yiping Shen, Xuyun Hu, Xiumin Wang, Yu Ding, Jian Wang, Juan Li, Yulin Chen, Guoqiang Li   +9 more
core   +1 more source

Validación funcional de variantes en LHCGR en pacientes con falla ovárica prematura no sindrómica

, 2017
La falla ovárica prematura (FOP) afecta al 1%-2% de las mujeres menores de 40 años. Se caracteriza por presencia de amenorrea y niveles elevados de gonadotropinas.
Jimenéz Rodriguez, Karen Marcela
core   +1 more source

Circulating LH/hCG receptor (LHCGR) may identify pre-treatment IVF patients at risk of OHSS and poor implantation [PDF]

, 2011
Background Successful pregnancy via in vitro fertilization (IVF) depends on the recovery of an adequate number of healthy oocytes and on blastocyst implantation following uterine transfer. Two hormones, LH and hCG, utilize a common LH/hCG receptor (LHCGR)
Mills Walter E, Banerjee, Subhasis, Nayini Krishnaveni P, Lockwood, Gillian M, Lockwood Gillian M, Mills, Walter E, Banerjee Subhasis, Chambers, Anne E, Nayini, Krishnaveni P, Chambers Anne E, Krishnaveni P Nayini, Anne E Chambers, Subhasis Banerjee, Gillian M Lockwood, Walter E Mills   +14 more
core   +1 more source

Genetic association between LHCGR variants and polycystic ovary syndrome: a meta-analysis

Journal of Assisted Reproduction and Genetics
The luteinizing hormone/choriogonadotropin receptor (LHCGR) is mapped at the 2p16.3 region, which was identified as a PCOS-susceptible locus in the first genome-wide association study (GWAS). Since then, several variants of LHCGR have been documented as susceptible loci for the development of PCOS, with striking differences due to diverse racial ...
Sukhjashanpreet Singh, Mandeep Kaur, Pallvi Thapar, Anupam Kaur   +3 more
openaire   +2 more sources

Signaling LH- e hCG-mediato in cellule target e linee cellulari trasfettate con LHCGR

, 2016
La gonadotropina corionica umana (hCG) e l’ormone luteinizzante (LH) sono ormoni glicoproteici che mediano eventi cruciali nello sviluppo sessuale e nella fertilità umana.
RICCETTI, LAURA
core  

Prevalence and genetic etiology of poly-cystic ovarian syndrome (PCOS) in Mauritania

Frontiers in Reproductive Health
BackgroundPolycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder characterized by polycystic ovaries, oligoanovulation, hyperandrogenism and infertility.
Marieme Elwafi, Abdi Ahmed, Abdi Ahmed, Omar Akhouayri, Ahmed Zein, Ahmed Zein, Hamma Abdelkader, Roughaya Selman, Ahmed Houmeida   +8 more
doaj   +1 more source