Results 111 to 120 of about 12,270 (235)

Bioinformatic Analysis of the Liability to the Hyperplastic Processes of the Uterus [PDF]

, 2015
This paper presents the results of bioinformatic analysis of five molecular genetic markers of 947 women with uterine hyperplasia and 988 women of the control ...
Altuchova, O. B., Churnosov, M. I., Krivoshei, I. V., Polonikov, A. V.   +3 more
core  

Pregnancy-induced Cushing’s syndrome with an adrenocortical adenoma overexpressing LH/hCG receptors: a case report

BMC Endocrine Disorders, 2020
Background Pregnancy-induced Cushing’s syndrome (CS) with an adrenocortical adenoma overexpressing luteinizing hormone (LH)/human choriogonadotropin (hCG) receptors (LHCGR) has been rarely reported in the literatures.
Shaohua Li, Chen Yang, Jing Fan, Yao Yao, Xiaomei Lv, Ying Guo, Shaoling Zhang   +6 more
doaj   +1 more source

Genetic Adaptation to Brackish Water and Spawning Season in European Cisco

Molecular Ecology, Volume 34, Issue 20, October 2025.
ABSTRACT How species adapt to diverse environmental conditions is essential for understanding evolution and the maintenance of biodiversity. The European cisco (Coregonus albula) is a salmonid that occurs in both fresh and brackish water, and this together with the presence of sympatric spring‐ and autumn‐spawning lacustrine populations provides an ...
Qiaoling Deng, Jake Goodall, Mikaela Bergenius Nord, Ignas Bunikis, Arianna Cocco, Bo Delling, Elisabet Einarsdottir, Julia Heintz, Henrik Lantz, Kerstin Lindblad‐Toh, Mai‐Britt Mosbech, Remi‐Andre Olsen, Stefan Palm, Mats E. Pettersson, Martin Pippel, Lucile Soler, Anti Vasemägi, Olga Vinnere Pettersson, Leif Andersson   +18 more
wiley   +1 more source

A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E ε4 allele

BMC Medical Genetics, 2008
Genetic and biochemical studies support the apolipoprotein E (APOE) ε4 allele as a major risk factor for late-onset Alzheimer's disease (AD), though ~50% of AD patients do not carry the allele.
Gleason Carey E, Meethal Sivan, Ahmadi M Reza, Haasl Ryan J, Johnson Sterling C, Asthana Sanjay, Bowen Richard L, Atwood Craig S   +7 more
doaj   +1 more source

Extensive admixture and selective pressure across the Sahel Belt [PDF]

, 2015
Genome-wide studies of African populations have the potential to reveal powerful insights into the evolution of our species, as these diverse populations have been exposed to intense selective pressures imposed by infectious diseases, diet, and ...
Adeola, Etefa, Etienne Patin, Gurdasani, Lamphear, Lewis, Luisa Pereira, Newman, Oliver-Bever, Patin, Pedro Soares, Petr Triska, Spencer, Teo, UNEP, Veronica Fernandes, Viktor Cerny, WHO   +17 more
core   +1 more source

High‐Fat and High‐Sugar Diet Induces Murine Premature Ovarian Failure by Promoting Mitochondrial Oxidative Phosphorylation Response

Food Science &Nutrition, Volume 13, Issue 9, September 2025.
Our study is the first to report the application of scRNA‐seq to analyze the ovarian landscape of HFHS‐fed mice and to verify that the HFHS diet induced POF in mice by activating the oxidative phosphorylation signal transduction pathway in the thecal cell, granulosa cell, and cumulus cell clusters in mouse ovarian tissues.
Kai Li, Yichao Wen, Zeyu Cui, Lele Ling, Chunxia Wang, Bimeng Zhang, Te Liu   +6 more
wiley   +1 more source

Semaphorin 3E‐Plexin‐D1 Pathway Downstream of the Luteinizing Hormone Surge Regulates Ovulation, Granulosa Cell Luteinization, and Ovarian Angiogenesis in Mice

Advanced Science, Volume 12, Issue 29, August 7, 2025.
The Semaphorin 3E (Sema3E)‐Plexin‐D1 pathway mediated by C/EBPα and C/EBPβ downstream of the luteinizing hormone (LH) surge plays important roles in the mouse preovulatory ovary. Timely activation and suppression of this pathway during the preovulatory stage are crucial for ovulation, corpus luteum formation, and proper angiogenesis.
Hanxue Zhang, Jimmy Dhillon, Paul D. Soloway, Bo Shui, Seoyeon Lee, Jennifer K. Grenier, Paul R. Munn, M. Cecilia Ljungberg, Rebecca B Williams, Rainer B. Lanz, Yu‐Hsiang Liao, Yi A. Ren   +11 more
wiley   +1 more source

Enhancing endometrial receptivity: the roles of human chorionic gonadotropin in autophagy and apoptosis regulation in endometrial stromal cells

Reproductive Biology and Endocrinology
Inadequate endometrial receptivity often results in embryo implantation failure and miscarriage. Human chorionic gonadotropin (hCG) is a key signaling molecule secreted during early embryonic development, which regulates embryonic maternal interface ...
Bin Wang, Mingxia Gao, Ying Yao, Haofei Shen, Hongwei Li, Jingjing Sun, Liyan Wang, Xuehong Zhang   +7 more
doaj   +1 more source

Clinical, biological and genetic analysis of prepubertal isolated ovarian cyst in 11 girls.

PLoS ONE, 2010
BackgroundThe cause of isolated gonadotropin-independent precocious puberty (PP) with an ovarian cyst is unknown in the majority of cases. Here, we describe 11 new cases of peripheral PP and, based on phenotypes observed in mouse models, we tested the ...
Raja Brauner, Anu Bashamboo, Sébastien Rouget, Marie Goulet, Pascal Philibert, Hélène Sarda-Thibault, Christine Trivin, Micheline Misrahi, Charles Sultan, Ken McElreavey   +9 more
doaj   +1 more source

Pivotal role of the muscle-contraction pathway in cryptorchidism and evidence for genomic connections with cardiomyopathy pathways in RASopathies [PDF]

, 2013
BACKGROUND: Cryptorchidism is the most frequent congenital disorder in male children; however the genetic causes of cryptorchidism remain poorly investigated.
Carlo V Cannistraci, Jernej Ogorevc, Minja Zorc, Peter Dovc, Tanja Kunej, Timothy Ravasi   +5 more
core   +1 more source