Results 141 to 150 of about 1,484,682 (382)

Enantioselective Miyaura Reaction by Desymmetrizing C(sp2)–B Cross‐Coupling of 1,1′‐Biaryl‐2,6‐diyl Bis(nonaflates)

open access: yesAngewandte Chemie, EarlyView.
A desymmetrization strategy for an enantioselective Miyaura‐type C(sp2)–B cross‐coupling to access highly enantioenriched, axially chiral biaryl boronic esters is disclosed. The enantiomeric excess of the chiral monoborylated product after reductive elimination is further improved by a downstream kinetic resolution, thereby converting the minor ...
Yao Xiao   +3 more
wiley   +2 more sources

The application of rigid gas permeable contact lenses after surgery for infantile nystagmus syndrome

open access: yesScientific Reports
The purpose of this study is to investigate the improvement in visual acuity when applying Rigid Gas Permeable Contact Lenses (RGPCL) compared to spectacles in patients after surgical treatment for infantile nystagmus syndrome (INS).
Yueying Jin   +5 more
doaj   +1 more source

Is Private Enforcement of EU Law through State Liability a Myth?:An Assessment 20 Years after Francovich [PDF]

open access: yes, 2012
This paper assesses the success of Member State liability as a tool for the private enforcement of European Union law. The argument made is that Member State liability, first established 20 years ago in the Francovich case, is not a suitable and reliable
Lock, Tobias
core  

Rüdin's Unpublished Family Study From the Early 1920s: “On the Inheritance of Manic‐Depressive Insanity”

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Ernst Rüdin, an important and controversial figure in the history of psychiatric genetics, published only one major empirical study on siblings of dementia praecox (DP) probands in 1916. He conducted a parallel study of siblings of probands with manic‐depressive insanity (MDI), but the resulting monograph, written in the early 1920s, was left ...
Kenneth S. Kendler, Astrid Klee
wiley   +1 more source

Adaptive Rhodium Catalysis with a Lewis‑Acidic Secondary Sphere for Divergent Hydrogenation of Propargylic Alcohols

open access: yesAngewandte Chemie, EarlyView.
Adaptive rhodium catalysis with a Lewis‐acidic secondary sphere enables divergent hydrogenation of propargylic alcohols into alkynes, allylic ethers, or alkenes. Catalyst design and condition‐dependent pathways provide practical guidance for chemoselectivity control.
Jiajun Wu   +5 more
wiley   +2 more sources

Performing a physiologically relevant test for cladribine tablets

open access: yesРазработка и регистрация лекарственных средств
Introduction. The introduction of devices – analogues of GIS (hereinafter–- Gastro-intestinal simulator) is one of the current ways to develop in-vitro assessment of the quality of solid dosage forms.
P. A. Losenkova   +8 more
doaj   +1 more source

Contractual liability [PDF]

open access: yesAnnals of "Spiru Haret". Economic Series, 2010
Any obligation entitles the creditor to claim the debtor to fulfil accordingly the performance he is bound to. An improper or delayed performance or the failure to perform by one party causes the other a prejudice, therefore entitling the latter to claim the former damages equivalent to the prejudice suffered.  
openaire   +2 more sources

EFFICIENCY OF EQUILIBRIA UNDER COMPARATIVE CAUSATION [PDF]

open access: yes
For past three decades or so, the negligence liability has been a major preoccupation of the economic analysis of liability rules. However, recently it has invited severe criticisms on several counts.
FRANCESCO PARISI, Ram Singh
core  

Schizophrenia Genetics Modulates Clinical Depressive Features

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Schizophrenia (SCZ) genetic liability, quantified by polygenic scores (PGS), may influence clinical phenotypes in major depressive disorder (MDD). We investigated the effect of the SCZ‐PGS derived from the latest SCZ genome‐wide association study (GWAS) on MDD symptom severity, comorbidities, and treatment outcomes.
Alessandro Serretti   +13 more
wiley   +1 more source

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