Results 161 to 170 of about 69,838 (265)

Incidence of Tetraplegia After Cervical Laminectomy Versus Laminoplasty: A Propensity Score Matched Analysis Using US Collaborative Network Database in TriNetX. [PDF]

Global Spine J
Chen H, Wang H.
europepmc   +1 more source

Design, synthesis and activity evaluation of tetrahydroisoquinoline‐based programmed cell death ligand 1 inhibitors

Smart Molecules, EarlyView.
Based on a 3D‐quantitative structure‐activity relationship pharmacophore model, structural optimization of Y6 yielded Y7f. Mechanistic studies revealed that Y7f acted as a programmed death receptor 1/programmed cell death ligand 1 (PD‐L1) interaction inhibitor by inducing PD‐L1 dimerization. Y7f restored T‐cell function.
Menglin Yu, Sen Cai, Yanyan Pan, Heshuang Wang, Fengwu Zhang, Aiyu Ma, Shixuan Lv, Xiuhan Guo, Shisheng Wang, Qiling Song, Chunyan Ma, Shuai Wang, Li Zhang, Jian Wang, Qingwei Meng, Yueqing Li   +15 more
wiley   +1 more source

Correction: Immunological mechanisms of low-grade systemic inflammation and its role in endometrial dysfunction in women with polycystic ovary syndrome. [PDF]

Front Immunol
Qu L, Li L, Yang L, Liu Y.
europepmc   +1 more source

BayesianKAN: A reaction condition optimization framework integrating Kolmogorov‐Arnold network and Bayesian optimization

Smart Molecules, EarlyView.
A novel BayesianKAN framework integrates Kolmogorov‐Arnold networks with Bayesian optimization to efficiently navigate complex factor spaces, accelerating the discovery of optimal reaction conditions for chemical synthesis. Abstract Efficient optimization of chemical reaction conditions is crucial for enhancing reaction yield and selectivity, yet ...
Juntao Wang, Yujing Zhao, Peiyu Yi, Liyuan Duan, Qingwei Meng, Qilei Liu   +5 more
wiley   +1 more source

Correction: Current research update on group B streptococcal infection related to obstetrics and gynecology. [PDF]

Front Pharmacol
Liu Y, Ai H.
europepmc   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source

Erratum to: S-palmitoylation of MTDH regulates ferroptosis resistance in breast cancer cell [Journal Lipid Research 67/1 (2026) 100953]. [PDF]

J Lipid Res
Pei S, Wang W, Feng T, Wang Q, Wang Y, Liu HX, Liang X, Piao HL.   +7 more
europepmc   +1 more source

A multifunctional near‐infrared dual‐channel off‐on‐off probe for sequential detection of fluoride and hypochlorous acid: Multimatrix applications

Smart Molecules, EarlyView.
This multifunctional, sequence‐specific probe (DHM) enables stepwise detection: fluoride triggers red/near‐infrared emission via cleavage, then hypochlorous acid induces blue fluorescence. It achieves fast, selective visual detection in environmental samples, foods, and in vivo models.
Tongtong Li, Xiaodong Zhang, Tong Yu, Dong Cai, Yabai Li, Shiyu Wu, Jingyi Gao, Yaqian Xu, Yihui Sun, Xuewei Pu, Fanjie Meng   +10 more
wiley   +1 more source