Results 101 to 110 of about 2,167,425 (344)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
DÜVEL- İ MUAZZAMA’NIN TANZİMAT’A BAKIŞI
Fırat Üniversitesi İlahiyat Fakültesi Dergisi, 2013 Bu makalede Düvel-i Muazzama’nın Tanzimat’a bakışını kısaca açıklamaya çalışacağız. Düvel-i Muazzama dediğimiz, 19. Yüzyılda Avrupa’nın 5 büyük devleti olan; İngiltere, Fransa, Rusya, Prusya ve Avusturya’dır.
Ramazan Ata
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Liberalism and liberal muslims
Journal of Philosophy, Culture and Political Science, 2021 Three central ideas in contemporary liberal political philosophy include: 1) liberty and equality represent the most basic political values; 2) legitimate political authority must be exercised on the basis of moral reasons that are compatible with liberty and equality; and 3) the burden of justification for political authority is on the state, not the ...
openaire +1 more source
FEBS Open Bio, EarlyView.Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
Political, economic and social characteristics of political parties' programmes in Serbia until 1918 [PDF]
Sociološki Pregled, 2019 In this paper, we merely begin to discuss the establishment of political ideas, beginnings of political thought and political streams at the end of the first half of the 19th century, as the basis upon which political parties were formed several decades ...
Kočović Dragoslav R.
doaj
Responsible Innovation for Decent Nonliberal Peoples: A Dilemma? [PDF]
, 2016 It is hard to disagree with the idea of responsible innovation (henceforth, RI), as it enables policy-makers, scientists, technology developers, and the public to better understand and respond to the social, ethical, and policy challenges raised by new ...
Wong, Pak-Hang
core
FEBS Open Bio, EarlyView.Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah +8 more
wiley +1 more source