Results 101 to 110 of about 651,292 (313)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Proceedings of the Joint Liberal Democracy Nepal and Nepal Study Center e-Seminar on The State’s Role in Private Sector Development in New Nepal

open access: yes, 2007
Liberal Democracy Nepal (LDN) and Nepal Study Center (NSC) jointly organized a month-long e-seminar entitled, “State’s Role in Private Sector Development” in February 2007.
Liberal Democracy Nepal, LDN
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Renewing Our Commitment to Liberal Education: Report of the Council on Liberal Education

open access: yes, 2008
Council on Liberal Education. (2008). Renewing Our Commitment to Liberal Education: Report of the Council on Liberal Education.
Council on Liberal Education
core  

Restrictive or Liberal Red‐Cell Transfusion for Cardiac Surgery

open access: yesNew England Journal of Medicine, 2017
D. Mazer   +30 more
semanticscholar   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Liberal values and New Commonwealth immigration, 1961-1981 [PDF]

open access: yes
Immigration to Britain from the New Commonwealth began in earnest in the late 1940s and the early 1950s. British governments, both Socialist and Conservative, found the issues raised by such immigration difficult to deal. with.
Deakin, Stephen
core  

Liberating Liberalism from Liberal Neutrality

open access: yes, 2007
Liberal neutrality is the idea that laws should not be based on religious or philosophical doctrines that not everyone accepts. The idea is closely related to the "liberal principle of legitimacy", which holds that laws are legitimate only if they are acceptable to people who are subject to them.
openaire   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

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