Results 41 to 50 of about 651,292 (313)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Liberal Arts Research Newsletters: 1985-1986

, 1985
College of Liberal Arts Office of Research Development. (1985). Liberal Arts Research Newsletters: 1985-1986.
College of Liberal Arts Office of Research Development
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Liberal Arts Research Newsletters: 1977-1978

, 1977
College of Liberal Arts Office of Research Development. (1977). Liberal Arts Research Newsletters: 1977-1978.
College of Liberal Arts Office of Research Development
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'Defensive liberal wars' : the global war on terror and the return of illiberalism in American foreign policy

, 2015
This paper offers an analysis of the illiberal practices and discourse of the Global War on Terror (GWoT) and demonstrates how the United States of America used the liberal argument as a qualitative metric of its success and failure in the GWoT.
Singh,Rashmi, Singh, R.
core   +1 more source

Liberal transfusion strategy to prevent mortality and anaemia-associated, ischaemic events in elderly non-cardiac surgical patients – the study design of the LIBERAL-Trial [PDF]

, 2019
Background: Perioperative anaemia leads to impaired oxygen supply with a risk of vital organ ischaemia. In healthy and fit individuals, anaemia can be compensated by several mechanisms. Elderly patients, however, have less compensatory mechanisms because
Kranke, Peter, Peter Kranke, Marion Ferner, Suma Choorapoikayil, Ana Kowark, Wittmann, Maria, Seifried, Erhard, Sascha Treskatsch, Oana Brosteanu, de Abreu, Marcel Gama, Peter Kienbaum, Kowark, Ana, Hasenclever, Dirk, Markus Velten, Thomas Ermert, Claudia Spies, Sixten Selleng, Francis, Roland, Meersch, Melanie, Michael Bauer, Gürtler, Karl-Heinz, Gueresir, Erdem, Laufenberg-Feldmann, Rita, Bogatsch, Holger, Markus M. Mueller, Marcel Baschin, Alexander Zarbock, Spies, Claudia, Sander, Michael, Velten, Markus, Marcel Gama de Abreu, Brosteanu, Oana, LIBERAL Collaboration Group, Stoppe, Christian, Christian Stoppe, Kai Zacharowski, Lindau, Simone, Simone Lindau, Bauer, Michael, Rita Laufenberg-Feldmann, Grünewald, Matthias Lars, Müller, Markus M., Eva Wittenmeier, Coburn, Mark, Kredel, Markus, Ermert, Thomas, Helf, Antonia, Melanie Meersch, Abreu, Marcelo Gama de, Gruenewald, Matthias, Ferner, Marion, Erhard Seifried, Holger Bogatsch, Roland Francis, Zacharowski, Kai, Antonia Helf, Karl-Heinz Gürtler, Timo Seyfried, Dirk Hasenclever, Wittenmeier, Eva, Choorapoikayil, Suma, Mueller, Markus M., Michael Sander, Meybohm, Patrick, Matthias Gruenewald, Treskatsch, Sascha, Zarbock, Alexander, Kienbaum, Peter, Markus Kredel, Patrick Meybohm, Selleng, Sixten, Maria Wittmann, Jenichen, Gregor, Mark Coburn, Gregor Jenichen, Güresir, Erdem Özer, Baschin, Marcel, Seyfried, Timo, Erdem Gueresir   +78 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Liberal Arts Research Newsletters: 1988-1989

, 1988
College of Liberal Arts Office of Research Development. (1988). Liberal Arts Research Newsletters: 1988-1989.
College of Liberal Arts Office of Research Development
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National Liberal Federation : proceedings in connection with the twenty-fourth annual meeting of the federation [PDF]

, 1902
leyds-p65-489.pdf created from original pamphlet in the WJ Leyds Collection held in the Africana Section of the Stellenbosch University Library and Information Service.Proceedings of the twenty-fourth annual meeting of the National Liberal Federation ...
National Liberal Federation (Great Britain)
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Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source