Results 71 to 80 of about 651,292 (313)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Liberal Arts Research Newsletters: 1983-1984
, 1983 College of Liberal Arts Office of Research Development. (1983). Liberal Arts Research Newsletters: 1983-1984.
College of Liberal Arts Office of Research Development
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Liberal Arts Research Newsletters: 1982-1983
, 1982 College of Liberal Arts Office of Research Development. (1982). Liberal Arts Research Newsletters: 1982-1983.
College of Liberal Arts Office of Research Development
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The best eight years yet : the Liberal government reports to the people
, 1956 The Best Eight Years Yet The Liberal Government Reports to the People"Manifesto of the Liberal Party", signed : Joseph R ...
Liberal Party of Newfoundland and Labrador
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Liberal legitimacy : a study of the normative foundations of liberalism
, 2008 This thesis is a critique of the prominent strand of contemporary liberal political theory which maintains that liberal political authority must, in some sense, rest on the free consent of those subjected to it, and that such a consensus is achieved ...
Rossi, Enzo
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Law and governance in Australian Aboriginal communities: liberal and neo-liberal political reason
, 2005 This paper examines Aboriginal governance in Australia in the 1890s, at a time when the mission station was the main instrument used to manage certain categories of Aboriginal person.
McCallum, David
core +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source