Results 101 to 110 of about 201,075 (295)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Seattle Gay Liberation Front Newsletter, Vol. 1, No. 6, 1971
, 1971 Homosaurus subject terms and some Contextual Notes were added to this item during the LGBTQ+ Materials Redescription Project in ...
Seattle Gay Liberation Front
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Seattle Gay Liberation Front Newsletter, Number 2, 1973
, 1973 Homosaurus subject terms and some Contextual Notes were added to this item during the LGBTQ+ Materials Redescription Project in ...
Seattle Gay Liberation Front
core
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Liberating services customers: The 21st century challenge
Innovar: Revista de Ciencias Administrativas y Sociales, 2011 Liberating services customers is the business challenge of the 21st century. Many service organizations have organizational structures and processes that are better designed to control customers than to serve customers.
Raymond P. Fisk
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Seattle Gay Liberation Front Newsletter, Vol. 1, No. 1, 1970
, 1970 Homosaurus subject terms and some Contextual Notes were added to this item during the LGBTQ+ Materials Redescription Project in ...
Seattle Gay Liberation Front
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Historia Crítica, 2011 This article analyzes and explains the interpretive framework that the Homosexual Liberation Front of Argentina (FLH, 1971-1976) constructed regarding (homo)sexuality, the family, and the politics of liberation through the articulation of "psi knowledge"
Guido Vespucci.
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