Results 121 to 130 of about 86,661 (264)

The six phases of prolonged veno-venous extracorporeal membrane oxygenator support: a conceptual framework. [PDF]

Crit Care
Hoffman KR, Diehl A, Nixon P, Yong SA, Fan E, Hodgson C, Burrell AJC.   +6 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Correction: Effects of exercise regimens on balance ability in older patients with osteoporosis: a systematic review and Bayesian network meta-analysis of randomized controlled trials. [PDF]

Front Physiol
Liu X, Chang M, Yuan H, Zheng X, Tian W, Li D, Liao D, Cui L.   +7 more
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

John Chilembwe’s Praxis

African Theological Journal for Church and Society
This study discusses the phenomenon of John Chilembwe’s praxis as a harbinger for the construction of public theology in Malawi. It articulates an apocalyptic, soteriological, ecclesiological, and missional vision in which the church is understood as a ...
Jones Hamburu Mawerenga
doaj  

Retrospective Study on Liberation in Dogs Undergoing Mechanical Ventilation for Longer Than 24 Hours. [PDF]

J Vet Emerg Crit Care (San Antonio)
McNally AE, Greensmith TD, Cortellini S.
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Correction: Elevated IL-17A level is associated with poor overall survival following immune checkpoint inhibitors combined with targeted therapy in hepatocellular carcinoma with hyperbilirubinemia. [PDF]

Front Immunol
Wang J, Pan S, Xiong C, Tian J, Wang Y, Yu Y, Wang S, Shen Y, Yang L, Liu X, Luan J, Jia M, Duan X, Wang F, Meng F.   +14 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Occult ovarian carcinoid in pregnancy: a case report and literature review. [PDF]

Front Oncol
Zhu Y, Wu Y, Chen Y.
europepmc   +1 more source