Results 21 to 30 of about 9,732 (219)

Can a librarian safeguard the reliability of the research?

open access: yesForum Bibliotek Medycznych, 2019
Contemporary science struggles with misconduct and unethical behavior of scientists. Craving for fame or other benefits that the publication in a prestigious scientific journal possibly entails, gives raise to various abuses.
Patrycja Kurowska
doaj   +1 more source

Roundtable: What is Holding Librarianship Back from Being more Inclusive of Visible Minorities

open access: yesPartnership: The Canadian Journal of Library and Information Practice and Research, 2018
For this issue, we asked three librarians and one MLIS candidate to respond to the following question: “According to Statistics Canada, 19.1% of the Canadian population identify themselves as visible minorities, but in the CAPAL census, only 9.1% of ...
Tamara Noor   +4 more
doaj   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

Information Literacy Practices and Perceptions of Community College Librarians in Florida and New York

open access: yesCommunications in Information Literacy, 2020
An online survey in Florida and New York of community college librarians with responsibility for information literacy instruction provides a snapshot of instructional objectives and practices, including librarians’ beliefs about students’ information ...
Heidi Julien   +4 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Prevalence of Musculoskeletal Pain and Burnout among Librarians of Shiraz University of Medical Sciences

open access: yesJournal of Rehabilitation Sciences and Research, 2020
Background: Musculoskeletal pain and burnout can influence the quality of services provided by librarians working in libraries; therefore, the present study has been designed to investigate the prevalence of musculoskeletal pain as well as the existence ...
Naghmeh Ebrahimi   +2 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

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