Results 31 to 40 of about 35,553 (269)
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
The Effect of Knowledge Management Systems and Knowledge Sharing on the Performance and Loyalty of Librarians [PDF]
علوم و فنون مدیریت اطلاعاتPurpose: Loyalty and satisfaction of employees are key factors for the success and survival of any organization, especially service-oriented organizations like public libraries.
Ali Biranvand +2 more
doaj +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
FEBS Open Bio, EarlyView.Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
Journal of Analytical Methods in Chemistry, 1997 This paper provides some initial considerations into the design and function of the Data Librarian. The first part (Liscouski, J., 1997, Journal of Automatic Chemistry, 19, 193‐197) described the need for the Librarian.
openaire +2 more sources
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Embracing diversity: when is a librarian not a librarian? [PDF]
The Australian Library Journal, 2016 AbstractIt is time for us to collectively embrace the diversity of the library profession and encourage students and graduates to understand that great employment opportunities present themselves outside the traditional library space. Our traditional library skills will always be required, but to maintain our relevance we must provide a greater ...
openaire +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Tacit Knowledge Sharing among Public Librarians: Case of Fars Province [PDF]
تحقیقات اطلاعرسانی و کتابخانههای عمومی, 2020 Purpose: A library and information specialist cannot rely only on his academic views. He can perform his job successfully only when he has access to his colleagues' scientific knowledge which is based on their experiences and uses it alongside his own ...
Leila Mozafari, Tahere Jowkar
doaj