Results 31 to 40 of about 374,467 (299)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

L’alfabetizzazione sanitaria: biblioteche e bibliotecari per il benessere dei cittadini

open access: yesAIB Studi, 2018
L’alfabetizzazione sanitaria è la capacità di ottenere, elaborare e capire informazioni sanitarie, in modo tale da partecipare attivamente, insieme ai medici, al processo decisionale per quanto riguarda la propria salute.
Vittorio Ponzani
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Krankenhausbibliotheken, Pharmabibliotheken, veterinärmedizinische Bibliotheken / Hospital libraries, pharmaceutical libraries, veterinary medical libraries

open access: yesGMS Medizin – Bibliothek – Information, 2011
The recent issue 1-2/2011 of GMS Medizin – Bibliothek – Information has a focus on hospital libraries, pharmaceutical libraries and veterinary medical libraries.
Bauer, Bruno
doaj  

Using Organization Theory to Explore the Changing Role of Medical Libraries [PDF]

open access: yes, 2012
This historical research review uses organization theory to describe and interpret the evolution of American hospitals, medical libraries, and the role of the professional librarian.
Fatkin, Kathy J
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Physician-Assisted Death: What Everyone Needs to Know

open access: yesJournal of the Medical Library Association, 2018
Physician-Assisted Death is recommended for academic medical centers and hospital libraries. It can be useful to libraries or college courses as a textbook introduction that addresses ethics and pro and con arguments.
Mary A. Wickline
doaj   +1 more source

HELIN Agreement for Integrated Library and Information Services, Amended 23 July 2008 [PDF]

open access: yes, 2008
Agreement on mission, governance, rights and responsibilities of participation, maintenance of effort, contracts, use of host computer for ILS, services to be performed by URI on behalf of HELIN, equipment and telecommunications, access to data, shared ...
HELIN Consortium. Board of Directors
core   +1 more source

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