Results 121 to 130 of about 6,125,574 (326)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Evaluation of Education Hospital Libraries in Mazandaran and Babol University of Medical Sciences according to Standards of Hospital Libraries

open access: yesمدیریت اطلاعات سلامت, 2014
Introduction: Progress in medical technology requires medical libraries to promote based on the references standards. The aim of this study was to evaluate the status of hospital libraries of Mazandaran and Babol University of medical sciences, on the ...
Nasrin Ebrahim Ghuchi   +2 more
doaj  

Open source repositories: Implications for libraries [PDF]

open access: yes, 2010
Software that is accepted as “Open source” should comply with 10 conditions which are itinerated in the paper. The paper subsequently describes the application of open source initiatives in the digital library context.
A.N., Zainab
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Special Libraries, September 1966 [PDF]

open access: yes, 1966
Volume 57, Issue 7https://scholarworks.sjsu.edu/sla_sl_1966/1006/thumbnail ...
Special Libraries Association
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Searching for studies: A guide to information retrieval for Campbell systematic reviews

open access: yesCampbell Systematic Reviews
This guide outlines general issues in searching for studies; describes the main sources of potential studies; and discusses how to plan the search process, design, and carry out search strategies, manage references found during the search process and ...
Heather MacDonald   +10 more
doaj   +1 more source

Special Libraries, April 1953 [PDF]

open access: yes, 1950
Volume 44, Issue 4https://scholarworks.sjsu.edu/sla_sl_1953/1003/thumbnail ...
Special Libraries Association
core   +4 more sources

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