Results 51 to 60 of about 5,959,618 (329)

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Heath Network Clinicians Use and Need for Clinical Information Sources: Results of a Survey [PDF]

, 2018
The Dana Medical Library, part of the University of Libraries system, with the support of the University of Vermont Health Network, assessed the needs of UVM Health Network clinicians for evidence-based clinical resources such as: medical databases ...
Burke, Marianne, Light, Jeanene
core   +1 more source

Library instruction in medical education: a survey of current practices in the United States and Canada

Journal of the Medical Library Association, 2018
Objective: The most recent survey on instruction practices in libraries affiliated with accredited medical institutions in the United States was conducted in 1996.
Amanda M. Nevius, A’Llyn Ettien, Alissa P. Link, Laura Y. Sobel   +3 more
doaj   +1 more source

Boston Medical Library [PDF]

The Boston Medical and Surgical Journal, 1922
n ...
openaire   +3 more sources

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Medical Information Literacy and the Quality of the Medical Services. [PDF]

, 2007
Information Literacy is the library operation which makes the library user able to search, retrieve, evaluate, select and use the information resources.
Katsirikou, Anthi
core  

Tıp ve Sağlık Bilimleri Kütüphaneciliğinde Ulusal ve Uluslararası Dernek Oluşumları / Formation of National and International Associations of Medical and Health Sciences Libraries [PDF]

Bilgi Dünyası, 2007
Medical libraries play important roles in classifying, storing andproviding access to medical information. Medical libraries are in steady development ever since 1850’s. This study reviews the formation of associations among modern medical libraries, and
Güssün Güneş
doaj  

Medizinbibliotheken: offen und innovativ aus Tradition

GMS Medizin – Bibliothek – Information, 2018
The focus of the current issue 3/2018 of GMS Medi Bibliothek – Information is on the annual conference 2018 of the German Medical Libraries Association in Oldenburg.
Bauer, Bruno
doaj   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source