Results 51 to 60 of about 656,072 (293)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Nivel de satisfacción de usuarios de la biblioteca de la Universidad de Ciencias Médicas de Las Tunas

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
Fundamento: la biblioteca universitaria es un espacio ideal para articular la ciencia, el conocimiento y la cultura.Objetivo: evaluar el nivel de satisfacción que poseen los usuarios de la biblioteca de la Universidad de Ciencias Médicas de Las Tunas ...
Edenny Reina Castillo Montes de Oca, Sandra Marín García, Nuria Gladys Álvarez González, Annia Martín Santos   +3 more
doaj  

'E' for exposed? Email and privacy issues [PDF]

, 1997
In March 1996, American Libraries featured a piece about a librarian at the University of California/Irvine whose supervisor intercepted her e-mail while she was absent on medical leave.
Gannon-Leary, Pat
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

In the Matter of Exemption to Prohibition on Circumvention of Copyright Protection Systems for Access Control Technologies: Hearing Before the U.S. Copyright Office, Library of Cong., May 6, 2009 (Statement of Roger V. Skalbeck, Geo. U. L. Library, on behalf of the American Association of Law Libraries, the Medical Library Association and the Special Libraries Association) [PDF]

, 2009
The American Association of Law Libraries, the Medical Library Association, and the Special Libraries Association submit the following comments on exemptions that should be granted pursuant to 17 U.S.C. § 1201 (a)(1)(C).
Skalbeck, Roger
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Information organization on the web site of medical library

Knjižnica, 2005
A library home page should be a document providing information about library, its various services to and activities for the users. The purpose of the present research was an evaluation of the actual state of-the-art of library home pages of Slovene ...
Marjeta Oven, Alenka Šauperl
doaj   +1 more source

Changes in library image creation on the example of the Main Library of the Medical University of Warsaw

Forum Bibliotek Medycznych, 2021
Nowadays, the libraries have to pay more attention to promotion than in the past, when occasional exhibitions, meetings with authors and posters advertising new books in the collection were enough.
Dagmara Szmajser-Chylarecka
doaj   +1 more source