Results 71 to 80 of about 674,146 (308)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Text 4 Health: Addressing Consumer Health Information Needs via Text Reference Service [PDF]

open access: yes, 2014
This study seeks to provide empirical evidence about how health-related questions are answered in text reference service in order to further the understanding of how to best use texting as a reference service venue to fulfill people’s health information ...
Ta Park, Van M.
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Progress Toward a National Serials Data System [PDF]

open access: yes, 1970
published or submitted for ...
Adams, Scott
core  

UK access to UK research [PDF]

open access: yes, 2007
Technological changes are providing opportunities for easier access to publicly-funded research. While these opportunities for easier access have been growing, concerns have been expressed that current business models are preventing their realisation ...
Friend, Frederick J.
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Von Dezentral zu Zentral: Würzburger Medizin-Bibliotheken / From decentralized to centralized: Medical Libraries in Würzburg

open access: yesGMS Medizin – Bibliothek – Information, 2009
At the University of Würzburg there are numerous small libraries at the institutes and clinics of the medical faculty. Several of them merged in the last years to a bigger unit. A central medical library can actually not be installed.
Klein, Diana
doaj  

Central medical library in Saudi Arabia : establishment and prospective development

open access: yesCybrarians Journal, 2005
A case study about the steps taken for the establishment of the Central Medical Library at the Ministry of Health in Kingdom of Saudi Arabia, it include historical background, location of the library, staff, collections, automation system, and gives ...
Mohammed Marghalani
doaj   +1 more source

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