Results 51 to 60 of about 9,322,260 (300)

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

A Study of the Quality of Services of Libraries of Qom University of Medical Sciences from the Point of View of Students and Academic Members Based on LibQUAL Model

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2017
Background and Objectives: Since academic libraries have a significant role in promoting educational and research purposes of universities, therefore, assessment of the quality of services provided based on the expectations and needs of users with ...
Zahra Abazari   +3 more
doaj  

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Strategien für Medizinbibliotheken [Strategies for medical libraries]

open access: yes, 2013
[english] The focus of the current issue 1-2/2013 of GMS Medizin – Bibliothek – Information is on strategies for medical libraries. Head librarians of medical libraries from Berlin, Bochum, Graz, Mainz, Mannheim, Münster and Vienna present their ...
Bauer, Bruno, Bauer, B
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Krankenhausbibliotheken, Pharmabibliotheken, veterinärmedizinische Bibliotheken / Hospital libraries, pharmaceutical libraries, veterinary medical libraries

open access: yesGMS Medizin – Bibliothek – Information, 2011
The recent issue 1-2/2011 of GMS Medizin – Bibliothek – Information has a focus on hospital libraries, pharmaceutical libraries and veterinary medical libraries.
Bauer, Bruno
doaj  

ON THE EFFECTIVENESS OF USING SCIENTIFIC AND MEDICAL INFORMATION

open access: yesАктуальные проблемы теоретической и клинической медицины, 2022
This article presents a comparative characteristic of scientific and medical information availability based on the results of practical healthcare specialists in the provinces of our republic.
M. N. Jainakbayev   +3 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy