Results 51 to 60 of about 277,055 (308)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

ON THE EFFECTIVENESS OF USING SCIENTIFIC AND MEDICAL INFORMATION

open access: yesАктуальные проблемы теоретической и клинической медицины, 2022
This article presents a comparative characteristic of scientific and medical information availability based on the results of practical healthcare specialists in the provinces of our republic.
M. N. Jainakbayev   +3 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Consumer health information : the role of hospital libraries [PDF]

open access: yes, 2001
The study examines the provision of consumer health information services by hospitals in New Zealand. An examination of the literature is followed by a detailed investigation of the New Zealand situation.
Oliver, Gillian, Bidwell, Pam
core  

Krankenhausbibliotheken, Pharmabibliotheken, veterinärmedizinische Bibliotheken / Hospital libraries, pharmaceutical libraries, veterinary medical libraries

open access: yesGMS Medizin – Bibliothek – Information, 2011
The recent issue 1-2/2011 of GMS Medizin – Bibliothek – Information has a focus on hospital libraries, pharmaceutical libraries and veterinary medical libraries.
Bauer, Bruno
doaj  

Information organization on the web site of medical library

open access: yesKnjižnica, 2005
A library home page should be a document providing information about library, its various services to and activities for the users. The purpose of the present research was an evaluation of the actual state of-the-art of library home pages of Slovene ...
Marjeta Oven, Alenka Šauperl
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Trends in hospital librarianship and hospital library services: 1989 to 2006. [PDF]

open access: yes, 2009
OBJECTIVE: The research studied the status of hospital librarians and library services to better inform the Medical Library Association's advocacy activities.
Thibodeau, Patricia L, Funk, Carla J
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Implementing digital resources for clinicians' and patients' varying needs. [PDF]

open access: yes, 2005
This paper presents an overview of several evidence-based medicine and patient information studies conducted across the UK health service over a 4 year period, investigating clinicians', managers', and patients' perceptions of digital resources ...
Blandford, Ann   +5 more
core   +1 more source

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